FANCD2与头颈部鳞状细胞癌
摘要
范可尼贫血是一种常染色体隐性遗传性疾病，以FA／BRCA通路失活导致DNA损伤修复功能障碍为分子基础，临床表现为先天性发育异常、进行性骨髓造血功能衰竭、染色体脆性增加以及高度的肿瘤易感性。
出处
《中国中西医结合耳鼻咽喉科杂志》
2013年第2期157-160,共4页
Chinese Journal of Otorhinolaryngology in Integrative Medicine
基金
四川省教育厅重点项目(12ZA076)
四川省卫生厅科研项目(120352)资助
参考文献27
-
1Stoepker C, Ha in K,Schuster B, et al .ST.X4, acoordinator of structure-specific endonucleases,is mutated in a new Fa neon i anemia subtype. Nat.Genet, 2011, 43(2); 138-141.
-
2Timmers C, Taniguchi T, Hejna J, et al. Positionalcloning of a novel Fanconi anemia gene,FAKXD2. Mol Cell,2001,7(2): 241 24H.
-
3Garcia-Higuera I, Taniguchi T, Ganesan S, et al.Interaction of tlie Fanconi anemia proteins andBRCA1 in a common pathway. Mol Cell, 2001,7(2): 249-262.
-
4Meetei AR, cie Winter JFt Medliurst AL, et al.A novel ubiquitin ligase is deficient in Fanconiane/nia. Nat Genet, 2003, 3-^(2): 165 170.
-
5Zliang Y, Zhou X, Zhao L, et al.UBE2VVinteracts with FANCL ancl regulates themonoubiquitination of Fanconi anemia proreinFANCD2.Mol Cells, 2011, 31(2): 113-122.
-
6Williams SA, Longerich S,Sung P, et al. The E3ubiquitin ligase RAL)18 regulates ubiciuitylationand chromatin loading of FANCD2 and FANCI.Blood, 2011. 117(19): 5078-5087.
-
7Zhi G, Wilson JB, Chen X,et al-Fanconi anemiacomplementation group FANCD2 protein serine331 phosphorylation is important for fanconianemia pathway function and BRCA2 interaction.Cancer Res, 2009,69(22); 8775 8783.
-
8Kim Parmar K,Huang M, et al. Inactivationof murine Uspl results in genomic instabilityand a Fanconi anemia phenotype.Dev Cell, 2009,16(2); 314-320.
-
9Cohn MA, Kowal P, Yang K, et al.A UAF1-containing multisubunit protein complex regulatesthe Fanconi anemia pathway. Mol Cell, 2007,28(5):786 797.
-
10Yang K, Moldovan GL, Vinciguerra P, et al.Regulation of the Fanconi anemia pathway bya SUMO-liKe delivery network,Genes Dev, 2011,25(17): 1847 1858.
-
1闫昕,郑以州.范可尼贫血基因与肿瘤易感性[J].中华血液学杂志,2009,30(7):496-498.
-
2彭惠媛,张颖,马冬惠,李燕玲.脆性组氨酸三联体基因及突变型p53基因在子宫颈癌组织中表达的关联性[J].中国基层医药,2011,18(21):2887-2889. 被引量：1
-
3张玉勤.一种有助于癌症研究的新酶[J].国外医学情报,2004,25(11):23-23.
-
4沈汉澄.如何辨别颈部肿块的性质[J].养生月刊,2002,23(4):161-161.
-
5Creaty.慢性淋巴细胞白血病新药:ofatumumab[J].中国处方药,2010,9(3):56-56.
-
6景阳,杨晓蓉,王宇娟,张文,刘晖,王敏.FHIT和Survivin在鼻腔鼻窦内翻性乳头状瘤中的表达及其意义[J].医学临床研究,2016,33(10):1876-1879. 被引量：2
-
7原伟光(综述),李殿俊(审校).FA／BRCA通路与乳腺癌[J].实用肿瘤学杂志,2010,24(4):317-319.
-
8陈涛.肠系膜囊肿的诊断和治疗体会[J].中国临床医学,2005,12(6):1088-1088.
-
9眼肿瘤[J].国外科技资料目录（医药卫生）,1997(6):138-138.
-
10邓娜,娄晔,于一冰,周珩,樊华.FANCD2在急性髓系白血病中表达[J].临床军医杂志,2016,44(6):586-588. 被引量：1
