摘要
目的评估6种肾脏深度估算公式对99mTc-DTPA肾动态显像测定肾小球滤过率(GFR)的影响。方法以232名北京地区健康居民为研究对象,分别采用双血浆法和99mTc-DTPA肾动态显像法测定GFR(GFRdt和GFRGates)。分析6种肾脏深度估算公式所得GFRGates与GFRdt间的相关性及一致性。结果公式1和5所得肾脏深度显著低于其他公式,公式3和6所得GFRGates与GFRdt的相关性最好(r=0.81)。公式1和5所得GFRGates与GFRdt一致性最差,差值均值分别为(-23.62±18.60)ml/(min.1.73m2)、(-20.66±18.00)ml/(min.1.73m2);公式3和4所得GFRGates与GFRdt一致性最好,差值均值分别为(-5.80±16.76)ml/(min.1.73m2)和(-3.81±17.87)ml/(min.1.73m2)。结论肾脏深度估算公式1、2、5准确性较差,其他公式结果差异较小;公式3、4和6均可用于临床,但公式3和4更优。
Objective To explore the impact of kidney depth obtained with 6 different estimation formulas on measurement of glomerular filtration rate （GFR） with ^99mTc-DTPA renal dynamic imaging. Methods Totally 232 Beijing community health residents were selected as the research subjects. Two-sample method and ^99mTc-DTPA dynamic renal imaging were used for determination of GFR （GFRdt and GFRGatoe, respectively）. Six estimation formulas were used to obtain kid- ney depth applying for calculating GFRGate, and GFRdt. Correlation and consistency of GFRGatoe and GFRdt were analyzed. Results The kidney depths derived from formula 1 and 5 were significantly lower than that of other 4 formulas. GFRat and GFRGates derived from formula 3 and 6 had the best correlation （r=0.81）. The consistency between GFRG derived from formula 1 and 5 and GFRdt was the worst, with the mean difference of （-23.62 ± 18.60）ml/（min ·1.73 m^2） and （-20.66± 18.00）ml/（min ·1.73 m^2）, respectively. The consistency between formula 3 and 4 derived GFRGates was the best with the mean difference of （-5.80＋16.76）ml/（min · 1.73 m^2） and （-3.81±17.87）ml/（min · 1.73 m^2）, respectively. Conclusion The accuracy of kidney depth estimation formula 1, 2, 5 are poor, while there are smaller differences among other formulas. Formula 3, 4 and 6 can be used clinically, whereas formula 3 and 4 are better.
出处
《中国医学影像技术》
CSCD
北大核心
2013年第5期800-804,共5页
Chinese Journal of Medical Imaging Technology
基金
科技部国际科技合作项目(2009DFA32960)
