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超极化激活环核苷酸门控阳离子通道4基因与心脏节律发生、发展及预后的关系 被引量：2

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摘要 超极化激活环核苷酸门控阳离子通道4基因在心脏节律的发生、发展及预后中有着重要的作用。研究表明,HCN4基因为窦房结起搏细胞产生自动节律的基础,也可影响心脏传导系统功能发育,其突变与病窦综合征有着密切的关系。通过HCN4起搏通道基因的转染技术构建生物心脏起搏器具有重要的生理意义。
作者 刘宇 汪艳丽 刘如秀
机构地区 中国中医科学院广安门医院心内科
出处 《中国心脏起搏与心电生理杂志》 2013年第2期178-180,共3页 Chinese Journal of Cardiac Pacing and Electrophysiology
基金 国家自然科学基金(项目编号:81173447)
关键词 心血管病学 超极化激活环核苷酸门控阳离子通道4基因 心脏节律 病窦综合征
分类号 R541.75 [医药卫生—心血管疾病]
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参考文献26

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二级参考文献64

共引文献36

同被引文献37

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中国心脏起搏与心电生理杂志
2013年 第2期

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