期刊文献+

一氧化碳中毒并发迟发性脑病的危险因素分析 被引量:2

Risk factors associated with delayed encephalopathy occurrence in carbon monoxide poisoning
原文传递
导出
摘要 目的探讨一氧化碳(co)中毒并发迟发性脑病(DE)的危险因素。方法回顾性分析249例CO中毒患者的病历资料,记录性别、年龄、CO接触时间、出现中毒症状至就诊时间、中毒后是否合并意识障碍、氧疗方式,采用单因素r检验筛选DE的危险因素,将有统计学意义的变量进行非条件Logistic回归分析。结果年龄和CO接触时间与DE的发生有关,60~75岁年龄段发生DE的风险是3~17岁年龄段的3.236倍,是18~59岁年龄段的2.119倍;CO接触时间≥12h发生DE的风险是〈12h的4.338倍。结论年龄≥60岁和CO接触时间≥12h是DE的独立危险因素。CO中毒的老年患者容易发生DE;及早脱离CO接触是预防DE发生的重要措施。 Objective To investigate the risk factors associated with delayed encephalopathy (DE) occurrence in carbon monoxide (CO) poisoning. Methods The clinical data of 249 patients with CO poisoning were retrospectively reviewed. Potential risk factors associated with occurrence of D E, including gender, age, duration of exposure to CO, time interval between onset and arrival in hospital, mental status after onset, oxygen therapy approach, were evaluated by univariate analysis of A~ test and multivariate Logistic regression analysis. Results Age and duration of exposure to CO was significantly related with occurrence of DE in patients with CO poisoning. The occurrence of DE in patients with CO poisoning with age 60 -75 years was 3.236 times and 2.119 times as much as that with age 3 - 17 years and 18 -59 years respectively. Occurrence of DE was 4.338 times in patients with duration of exposure to CO 312 hours compared to that 〈 12 hours. Conclusions Age ~ 60 years and duration of exposure to CO ≥12 hours are independent risk factors for developing D E. Old patients have a inclination to develop D E. To evacuate patients from CO environment timely is important for preventing from DE.
出处 《中国医师进修杂志》 2013年第13期21-23,共3页 Chinese Journal of Postgraduates of Medicine
关键词 一氧化碳中毒 危险因素 迟发性脑病 Carbon monoxide poisoning Risk factors Delayed encephalopathy
  • 相关文献

参考文献1

二级参考文献11

  • 1孟宪辉,耿月华,王怀敏.急性一氧化碳中毒后的迟发性脑病[J].中国现代神经疾病杂志,2004,4(6):389-390. 被引量:2
  • 2陈志强,杨文君,蔡磊.急性一氧化碳中毒后迟发性脑病的临床表现和CT及MRI研究[J].中华劳动卫生职业病杂志,2005,23(6):438-441. 被引量:33
  • 3Weaver LK. Carbon monoxide poisoning[J]. N Engl J Med, 2009,360(12) :1 217-1 225.
  • 4Kwon OY,Chang SP, Ha YIR,et al. Delayed post anoxic en- eephalopathy after carbon monoxide poisoning[J]. Emergency Med,2007,21 (2) :250-251.
  • 5Huijun Hu,Xiaowen Pan,Yi Wan,et al. Factors affecting the prognosis of patients with delayed encephalopathy after acute carbon monoxide poisoning[J1. Am J Emergen Med, 2011,29 (3) :261-264.
  • 6Carlsson CA, Von Essen C, Lofgren J. Factors affecting the clinical course of patients with severe head injuries. 1. Infulu- ence of biological factors. 2. Significance of posttraumatic co- ma[J], J Neurosurg,1968,29(2),242-251.
  • 7Chang KH, Han MH, Kim HS, et al. Delayed encephalopathy after acute carbon monoxide intoxication: MR imaging features and distribution of cerebral white matter lesions[J]. Radiolo- gy,1992,184(1):117-122.
  • 8Wang P,Zeng T,Chi Z. Recovery of cognitive dysfunction in a case of delayed encephalopathy of carbon monoxide poisoning after treatment with donepezil hydrochloride[J]. Neurol India, 2009,57(4) :481-482.
  • 9杨延芳,任立军,郝强,刘春红,张文英,张士喜.一氧化碳中毒迟发性脑病的病程及预后[J].卒中与神经疾病,2007,14(4):220-222. 被引量:18
  • 10曾员英,胡慧军,万毅,杨平地,潘晓雯.急性一氧化碳中毒迟发性脑病预后影响因素分析[J].中华航海医学与高气压医学杂志,2008,15(3):152-155. 被引量:19

共引文献64

同被引文献19

引证文献2

二级引证文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部