摘要
本文对今年来国内外研究中药肠吸收的文献进行了检索和分析,介绍了目前常用的研究中药肠吸收的方法和模型,并对中药有效单体成分的肠吸收、中药单味药和复方的肠吸收以及影响中药肠吸收的因素进行了综述,在此基础上介绍了促进中药肠吸收的策略。旨在为提高中药的口服生物利用度、改进中药剂型、发现中药新药和临床合理使用中药提供参考。
This review analyzed domestic and foreign literatures on intestinal absorption, introduced the current methods and models commonly used in traditional Chinese medicine researches focused on intestinal absorption, and their efficacy and impact on monomer components intestinal absorption of single herbs and compound Chinese medicine, in order to promote the efficacy of intestinal absorption of traditional Chinese medicine, provide a reference for improving the oral bioavailability of Chinese medicine, improve Chinese medicine formulations, new Chinese medicine and clinical rational use of traditional Chinese medicine.
出处
《药品评价》
CAS
2013年第6期30-35,共6页
Drug Evaluation
基金
中央高校基本科研业务费资助
项目名称:基于Caco-2细胞CES表达缺陷的改良及用于酯类前药体外吸收评价的的研究
编号:HUST:2012QN182
关键词
中药
药动学
肠吸收
药物转运体
Traditional Chinese Medicine
Pharmacokinetics
Intestinal Absorption
Drug Transporter