新生儿胎儿口腔前庭粘膜乳头状结构的初步观察

PRELIMINARY OBSERVATION OF PAPILLIFEROUS PROJECTION ON THE VESTIBULE OF MOUTH IN EMBRYOS AND INFANTS (ABSTRACT)

本文介绍部分胎儿及新生儿口腔前庭粘膜所见的与正常粘膜色泽相同的乳头状突起的观察结果。资料包括22例胎儿与4例新生儿的尸体及287例新生儿的口腔前庭粘膜所见。287例新生儿中粘膜有乳头状结构者120例。男性142例中阳性者61例(42.9％);女性145例中阳性者59例(40.7％)。男女总例数与阳性数之比均约1:1,无明显性别差。此结构在上、下唇的分布不均,下唇多于上唇,双侧基本对称。从随访及胎儿的观察结果表明此结构在妊娠3～4个月即已出现,随孕龄增长乳头逐渐发育生长,其表面被覆与周围相延续的鳞状上皮,有毛细血管及结缔组织伸入组成中轴,其结构与舌背丝状乳头相似,在生后10天左右此结构即渐消退。对此结构我们尚未在书刊中查到有关资料,其生物学意义有待于进一步探讨。

Papilliferous projections on vestibular mucous membrane in infantsand embryos were recommended. 22 embryonal corpses and 4 newborninfant corpses as well as 287 newborn infants were examined. Speci-mens taken from corpses were examined with stereo-microscopy andscanning electron microscopy to observe their surface structure, andwith light microscopy to observe histological structure. Infants withpapilliferous projections were followed up in order to find what thepapilliferous projections would change into normal. The resultsare as follows: Among 22 embryo corpses there were 3 cases withthe papilliferous projections 120 cases among 287 newborn infants(142 males; 145 females), (41.8%). There was no obvious sexdifference. The numbers of the papilliferous projections in the lowerlip were more than those in the upper lip. The numbers in the leftside were equal to those in the right side of the lip. The results alsoshowed that this constraction appeared in 3～4 months embryos,gradually and disappeared in 10 days or so after birth. The results oflight microscopy examination: the surface of the papilliferous proje-ctions were covered with stratified squamous epithelium capillaryblood vessels and dense connective tissue extended into the projectionand consist the axis, so the structure of the papilliferous projectionsappeared similar to the filiform papillae on the dorsum of the tongue.Until now have not find any report about this article. The biologicalsignificane still remains a question to be resovlved.