高压氧治疗视网膜静脉阻塞后黄斑囊样水肿的初步报告

TREATMENT OF CYSTOID MACULAR EDEMA SECONDARY TO RETINAL VEIN OCCLUSION WITH HYPERBARIC OXYGEN, A PRELIMINARY REPORT

根据随机对照原则,对26眼(治疗组14眼)继发于视网膜静脉阻塞后的黄斑囊样水肿进行了前瞻性高压氧治疗。治疗组在治疗前后平均视力提高3.7行(2～6行),有效率100％,对照组提高0.18行(1～2行),有效率18％,两组比较有显著性差异。随访3～6个月,治疗组视力稳定或继续上升。但荧光造影显示治疗前后黄斑囊样水肿的变化无明显差异。认为高压氧治疗本病,适应症宽,副反应少,增加缺血视网膜的氧供,促使血管收缩,减少渗漏,是一种增进视力,缩短病程的较好的治疗方法。

A controlled and randomized prospective study was established to estimate the effect of hyperbaric oxygen (HBO) treatment for the 26 eyes (HBO group 14 eyes) of cystoid macular edema (CME) secondary to retinal vein occlusion (RVO). The visual acuity of the patients was improved(between 2-6 lines, average 3.7 lines)after the treatment, and there was a statistical significance between the HBO group and the controlled group. The study also showed the curative effect was quitely stable. But fluorescein-angioraphy showed that there was no prominent reduction in leakage of dye from the perifoveal capillaries after the HBO treatment. It is demonstrated that HBO therapy has many indications and has few side effect. HBO increases amounts of oxygen, constricts blood vessels, reduces the leakage from the perifoveal capillaries and resolves the macular edema. It appears that HBO treatment is an effective modality to improve visual acuity and reduce the nature course of the CME patients.