泌尿系统感染患者抗菌药物使用状况调查和细菌耐药监测研究

Use of antimicrobial agents survey and antimicrobial resistance monitoring study of patients with urinary tract infection

目的对泌尿系统感染患者抗菌药物的使用状况进行调查,并监测主要病原菌对常用抗菌药物的耐药率。方法收集泌尿系统感染患者的临床治疗资料,进行抗菌药物使用状况的调查。取患者中段尿液进行药敏试验,并研究主要泌尿系统感染病原菌对常用抗菌药物的耐药率。结果本组患者治疗期间所使用的抗菌药物例次由高到低依次为:头孢呋辛钠、阿米卡星、头孢唑肟、头孢他啶、头孢曲松以及其他。泌尿系统感染的病原菌主要有:大肠埃希菌、肺炎克雷伯菌、粪肠球菌、屎肠球菌、变形杆菌等。结论对泌尿系统感染患者抗菌药物使用状况和细菌耐药状况进行监测研究对提高抗菌药物的合理使用水平具有重要的意义。

Objective To survey the use of antimicrobial agents of the patients with urinary tract infection, and then monitor the resistance rates of main pathogens to the commonly used antibiotics. Methods The clinical treatment materials of the patients with urinary tract infection were gathered and conducted the survey of the antimicrobial drug use. Patients＇ midstream urine drug susceptibility was tested, and the main urinary tract infections pathogens to commonly used antibiotics resistance rates were studied. Results The group of patients during treatment with antimicrobial use cases descending order： cefuroxime sodium, amikacin, ceftizoxime, ceftazidime, ceftriaxone, and other. Urinary tract infection pathogens： Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, Enterococcus feces, Proteus, etc. Conclusion To survey the antimicrobial drug use and monitor the antimicrobial resistance is helpful to the improvement of level of rational use of antimicrobial drugs.