戊酸雌二醇配伍安宫黄体酮序贯治疗药物流产不全的疗效观察

The observation of estradiol valerate cooperating with MPA sequential treatment for medical abortion not all

目的观察戊酸雌二醇配伍安宫黄体酮序贯治疗对药物流产不全的疗效。方法将药物流产不全的120例患者随机分成3组,各组40例,残留物平均直径≤1.5cm者分为A、B组,残留物平均直径>1.5cm且≤3.1cm者为C组,A组和C组采用戊酸雌二醇配伍安宫黄体酮序贯治疗,B组采用新生化冲剂治疗,比较3组的临床疗效。结果 A组止血率(100.0%)和有效率(92.5%)明显高于B组止血率(35%)和有效率(35%),A组有效率高于C组(57.7%),差异有统计学意义(P<0.01),A组与C组止血率差异无统计学意义(P>0.05)。结论戊酸雌二醇配伍安宫黄体酮序贯治疗药物流产不全的疗效肯定,残留物平均直径>1.5cm疗效降低。

Objective To observe the curative effects of estradiol valerate cooperating with MPA sequential treatment for medical abortion not all. Methods Put the 120 cases which uterine cavity residue after medical abortion randomly into three groups. 40 cases each group. Mean diameter less than or equal to 15 mm into group A and B, mean diameter more than 15 mm and less than or equal to 31 mm into group C. Group A and group C used estradiol valerate cooperating with MPA sequential treatment, group B with new bio chemical granule treatment , comparing the differences between each group. Results The haemorrhage rate and of group A （100%）and efficient of group A （92.5%） obviously higher than those in the control group B （35.0%）, difference is statistically significant （P 〈0.01）. Efficient of group A obviously higher than those in the control group C （57.7%）, difference is statistically significant （P 〈0.01）. There was no statistically significant difference between haemorrhage rate of group A and group C （P 〉0.05）. Conclusion The effects of estradiol valerate cooperating with MPA sequential medical abortion not all is assured. Residual mean diameter more than 15 mm is less effective.