复发性卵巢癌再次铂类化疗患者预见性呕吐相关指标观察

Related Indicators Observed of Predictability Vomiting in Patients with Recurrent Ovarian Cancer for Platinum Chemotherapy Again

目的：观察复发性卵巢癌再次铂类化疗患者预见性呕吐（ANY）相关指标。方法：选择2010-01/2012-01于我科接受再次铂类化疗的复发性卵巢癌患者（复发化疗组）36例,另行选择38例同期住院接受铂类化疗方案的初诊卵巢癌患者（初诊化疗组）为对照组。第二疗程开始前,两组患者分别接受了＂ANY等级指标＂和＂恶心问卷（NP）＂评估。结果：复发化疗组的ANY患病率及ANY等级指标均明显多于初诊化疗组,同时复发化疗组NP问卷中各因子分及总分也明显高于后者（P均〈0.01~0.05）。结论：复发性卵巢癌再次铂类化疗患者ANY患病率、ANY等级指标及NP问卷评分均有显著增加。

Objective： To observe the relevant indicators in patients with the predictability vomiting（ANY） of recurrent ovarian cancer with platinum chemotherapy again.Methord：Selected 36 cases hospitalized from 2010-01 to 2012-01 accepted again platinumbased chemotherapy in our department to accept recurrent ovarian cancer（recurrence chemotherapy group）,In the same period the alternative 38 cases hospitalized for platinum-based chemotherapy in patients with newly diagnosed ovarian cancer（newly diagnosed chemotherapy group） for the control group.Before the second course of treatment,two groups of patients were treated with ANY level indicators and the nausea questionnaire（NP） assessment.Result：ANY prevalence,and ANY level indicators of recurrent chemotherapy group level indicators were significantly more than the first diagnosed chemotherapy group,at the same time,in recurrent chemotherapy group,the NP questionnaire factor scores and total scores were significantly higher than the latter（P0.01~0.05）.Conclusions： Prevale nce of recurrent ovarian cancer re-platinum chemotherapy in patients with ANY,ANY level indicators and NP Questionnaire score were significantly increased.