急性脑卒中患者医院获得性肺炎58例的治疗及疗效因素分析

Treatment of 58 Hospital-acquired Pneumonia Cases Following the Stroke andAnalysis on Factors Influencing Efficacy

目的:对比观察对照组与观察组治疗急性脑卒中患者医院获得性肺炎(HAP)的疗效,并分析影响临床疗效的因素。方法:58例患者分为两组,对照组29例:合理使用抗生素+综合干预治疗,观察组29例在对照组治疗方案的基础上合用胸腺肽α1。比较两组治愈率和不良反应发生率;并通过单因素分析和多因素回归分析探讨影响疗效的因素。结果:与对照组比较,观察组治愈率具有统计学意义(P<0.05),不良反应发生率无显著性差异(P>0.05);患者年龄和感染多重耐药菌是影响疗效的主要因素。结论:观察组治疗方法疗效确切,安全性好;合理使用抗生素与提高病人免疫力在治疗中至关重要。

Objective： To comparative observe efficacy of treatment of hospital-acquired pneumonia（HAP） following the stroke in the comparison group and the observation group.Methods： The 58 patients were divided into observation group and comparison group,it has been used in 29 patients of the comparison group what was rational use of antibiotics and intervention comprehensive,and 29 patients of the observation group have been used of thymosin α1 base on the treatment of comparison group.The cure rate and incidence of adverse reactions were compared between the two groups,The influencing efficacy factors have been analyzed by single factor analysis and Logistic regression analysis.Results： Compared with the comparison group,the differences was no statistically significant（P0.05） when the ncidence of adverse reactions was tested in observation group,and it was statistically significant（P0.05）when the r cure rate were tested.The age of and patients infected with multiple resistant were the main factors influencing efficacy.Conclusion： The treatment method is effective and safe used in the observation group.It is vital in the treatment,including the rational use of antibiotics and improved patient immunity