单纯抗凝治疗次大面积肺栓塞的临床疗效观察

Pure Anticoagulation Times the Clinical Curative Effect of Large Pulmonary Embolism Observation

目的:探讨单纯抗凝治疗次大面积肺栓塞的临床疗效。方法:将我院2010年6月到2012年6月收治的次大面积肺栓塞患者30例,随机分为溶栓加抗凝组与单纯抗凝组,溶栓加抗凝组给予尿激酶溶栓及抗凝药物治疗;抗凝组仅给予肝素联合华法林进行抗凝治疗。治疗后比较两组的临床疗效,动脉血气指标(PaO2及PaCO2)变化,进行疗效的对比。结果:单纯抗凝组治疗后的PaO2及PaCO2变化与溶栓加抗凝组相比无明显差异(P>0.05);单纯抗凝组的显效率与总有效率较溶栓加抗凝组相比亦无明显差异(P>0.05)。结论:次大面积肺栓塞单纯抗凝治疗与溶拴加抗凝治疗相比无显著差异,且单纯抗凝治疗较溶拴加抗凝治疗出血风险率小。

Objective： To investigate the pure anticoagulation times the clinical curative effect of large pulmonary embolism.Methods： Our June 2010 to June 2012 of the time were large pulmonary embolism with 30 cases were randomly divided into thrombolysis group and anticoagulation group,thrombolysis were given NiaoJiMei fibrinolytic therapy;Anticoagulation group give heparin joint law shenyang antithrombotic therapies.After treatment compared with two groups of clinical curative effect,arterial blood gas index（PaO2 and PaCO2） change,the efficacy of contrast.Results： After treatment group of anticoagulant PaO2 and PaCO3 is obviously superior to thrombolysis group（P 0.05）;Anticoagulation group of significant efficiency and the total effective rate were significantly higher than that of thrombolysis group（P0.05）.Conclusion： Time large pulmonary embolism pure anticoagulation and thrombolytic anticoagulant therapy compared with no significant differences,and pure anticoagulation a thrombolytic and anticoagulation bleeding risk rate is minor.