积极营养支持对老年COPD患者临床疗效的影响

Active nutritional support on clinical outcome in aged patients with COPD

目的探讨积极营养支持对老年慢性阻塞性肺疾病(COPD)患者临床疗效的影响。方法将128例老年COPD患者依据住院单双日随机分为观察组和对照组各64例,两组均常规行抗炎、解痉平喘、止咳化痰及吸氧等治疗。此外,观察组给予氨基酸、脂肪乳、白蛋白及葡萄糖等积极营养支持,对照组采用普通膳食。比较两组临床总有效率、平均住院天数、肺功能、营养状况、血清尿酸、住院期间病死率及并发症等指标。结果观察组临床总有效率明显高于对照组(P<0.05),平均住院天数明显少于对照组(P<0.05),营养状况、肺功能、血清尿酸指标优于对照组(P<0.05)。结论在常规治疗基础上,积极营养支持可明显提高老年COPD患者的临床疗效,改善患者营养状况、肺功能,缩短住院天数。

Objective To investigate the clinical effects of active nutritional support on clinical outcome in aged patients with COPD. Methods 128 aged patients with COPD were randomly divided into two groups： the control group（64 cases） and the observation group （64 cases）, the two groups accepted the same anti -infection, antispasmodic asthma, cough and phlegm, and oxygen treatment. In addition, the observation group were given active nutritional support, such as amino acids, fat emulsion, albumin, and glucose, while the control group were giren normal diet. The total rate of clinical effective, The average hospitalization days, lung function, nutritional status, serum uric acid, the rate of mortality and complications were observed of the two groups during hospitalization. Results Compared with the control group, the total effective rate was higher and the average length of stay was less in the intervention group （ P 〈 0.05） ; nutritional status, lung function, serum urine acid in the intervention group were superior to the control group （P 〈 0.05）. Conclusion On the basis of routine treatment, active nutritional support for aged patients with COPD could raise the therapeutic effect, improve nutritional status and lung function, shorten the time of hospitalization.