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血氧水平依赖磁共振成像评价慢性肾脏病氧合水平的研究进展

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摘要 20世纪90年代,Ogawa等[1]运用高场磁共振设备首次描述了鼠脑部血氧水平依赖（blood oxygen level dependent,BOLD）MR信号产生的机制。BOLD-MRI随即被广泛地应用于中枢神经功能成像。近年来,由于肾脏皮、髓质血供及氧合特点以及肾髓质缺血在肾功能衰竭中的重要作用,
作者 李成 房向东 涂卫平
机构地区 南昌大学第二附属医院肾内科
出处 《实用医学杂志》 CAS 北大核心 2013年第9期1531-1533,共3页 The Journal of Practical Medicine
关键词 血氧水平依赖 慢性肾脏病 磁共振成像 氧合 中枢神经功能 髓质缺血 磁共振设备 Ogawa
分类号 R445.2 [医药卫生—影像医学与核医学]
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参考文献18

  • 1Ogawa S, Lee T M, Kay A R, et al. Brain magnetic resonance imaging with contrasl dependent on blood oxygenation [J]. Proc Natl Acad Sci USA, 1990,87(24) :9868-9872.
  • 2Xin-Long P, Jing-Xia X, Jian-Yu L, et al. A preliminary study of blood- oxygen-level-dependent MRI in patients with chronic kidney disease [J]. Magneic Resonance Imaging, 2012,30 (3) : 330-335.
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  • 6Inoue T, Kozawa E, Okada H, et al. Noninvasive evaluation of kidney hypoxia and fibrosis using magnetic resonance imaging [J]. J Am Soc Nephrol, 20 1 1,22 (8) : 1429-1434.
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二级参考文献21

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  • 3Nangaku M,Inagi R,Miyata T,et al.Angiotensin-induced hypoxia in the kidney:functional and structural changes of the renal circulation.Adv Exp Med Biol.2007;618:85-99.
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  • 6Li LP,Storey P,Pierchala L,et al.Evaluation of the reproducibility of intrarenal R2* and △R2* measurements following administration of furosemide and during waterload.J Magn Reson Imaging.2004;19(5):610-616.
  • 7Zuo CS,Rofsky NM,Mahallati H,et al.Visualization and quantification of renal R2* changes during water diuresis.J Magn Reson Imaging,2003;17(6):676-682.
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  • 9Li LP,Ji L,Santos EA,et al.Effect of nitric oxide synthase inhibition on intrarenal oxygenation as evaluated by blood oxygenation level-dependent magnetic resonance imaging.Invest Radiol.2009;44(2):67-73.
  • 10Pedersen M,Dissing TH,Morkenborg J,et al.Validation of quantitative BOLD MRI measurements in kidney:application to unilateral ureteral obstruction.Kidney Int,2005;67(6):2305-2312.

共引文献7

实用医学杂志
2013年 第9期

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