3种常用避孕节育技术对已婚育龄妇女生活质量的影响

The impact of three kinds of contraceptives on quality of life in women at reproductive age

目的:分析比较育龄妇女使用元宫铜300宫内节育器(IUD)、复方甲地孕酮避孕针和两根型皮下埋植剂3个月后生活质量的变化情况。方法:2007年7月～2008年12月在我国8个省的20所县级计划生育服务站开展多中心临床研究。以在每所服务站就诊要求使用上述3种避孕方法的健康育龄妇女为研究对象,采用SF-36量表调查妇女使用避孕措施前和使用后3个月时的生活质量状况。结果:20个研究中心共纳入1356例已婚育龄妇女,其中446例使用元宫铜300IUD、610例使用皮下埋植剂、300例使用避孕针避孕。使用避孕措施3个月后,IUD组和避孕针组生活质量总得分较基线得分略增加,而使用皮下埋植剂组生活质量总得分略下降。调整基线得分、所在地区、职业、收入、产次及末次使用避孕方法,使用皮下埋植剂和避孕针组生活质量得分增加值略低于元宫铜组。结论:3种避孕方法对妇女生活质量的影响均较小,使用元宫铜300IUD者生活质量改善情况略优于使用避孕针和皮下埋植剂者。

Objective： To compare the effects of GT300 intrauterine device （IUD） , compound megestrol acetate injection （Injection）, and Norplant implant （Norplant） on the quality of life among chinese users at reproductive age. Methods： A muhicenter clinical trial was conducted in 25 county - level family planning clinics in 8 provinces. The women who were see-king for contraceptives mentioned above were enrolled. The chinese version of the 36 - items short form health survey （ SF - 36） was used to evaluate the quality of life before and 3 months after contraceptive use. Results： A total of 1356 women at re-productive age were enrolled in 20 clinics, among whom 446 women used IUD, 610 used Injection and 300 used Norplant. The total score of SF-36 slightly improved 3 months after both IUD insertion and Injection use, while it showed a slight de-crease 3 months after Norplant use. After adjusting the baseline score, residence, occupation, income, parity, and contracep-tive methods used last time, the improvements in the total score 3 months after both Norplant and Injection use were less than that in IUD users. Conclusion： No significant change on quality of life is found before and after IUD, Injection or Norplant use, while the quality of life among IUD users improves.