动态血糖监测联合胰岛素泵短期治疗老年2型糖尿病

Observation on the Efficacy of Continuous Glucose Monitoring Combined with Short-term Insulin Pump for the Treatment of Elderly Patients with Type 2 Diabetes Mellitus

【目的】观察动态血糖监测系统（CGMS）和胰岛素泵皮下持续输注（CSII）组成的“双c”方案应用在老年2型糖尿病（T2DM）患者血糖控制中的疗效及安全性。【方法】选取老年T2DM患者90例，随机分为两组，CSII＋CGMS为观察组，45例，CSII＋多次指尖血糖检测血糖为对照组，45例。观察两组治疗后患者血糖值的变化、波动幅度、达标时间、胰岛素用量、低血糖发生率。【结果】观察组的患者血糖控制更平稳，达标时间更短，胰岛素用量更少，低血糖的发生率更低（P〈O．05）。【结论】动态血糖监测联合胰岛素泵短期治疗是老年T2DM患者更有效、更安全的治疗方案。

[Objective]To observe the efficacy and safety of ＂double C＂ program including continuous glucose monitoring system（CGMS） and continuous subcutaneous insulin infusion（CSII） in blood glucose control of elderly patients with type 2 diabetes mellitus（T2DM）. [Methods]Ninety elderly patients with T2DM were chosen and ran- domly divided into observation group（CSII＋ CGMS, n = 45） and control group （CSII-- multiple fingertip blood glu- cose testing blood glucose, n =45）. The change of blood glucose value, fluctuation amplitude, the time up to the standard, insulin dose and the incidence of hypoglycemia in patients after treatment were observed. [Results]In ob- servation group, blood glucose control in observation group was more stable, and the time up to the standard was shorter, and insulin dose was smaller, and the incidence of hypoglycemia was lower（ P 〈0.05）. [Conclusion] CGMS combined with short-term CSII for the treatment of elderly patients with T2DM is more effective and safer.