雾化吸入加味枳术煎对乙直肠癌术后肠道功能的影响

Effect of Atomization Inhalation o f Modified Zhizhu Decoction on Intestinal Function Recovery in Postoperative Patients with Colorectal Cancer

【目的】观察氧驱动雾化吸入加味枳术煎对乙状结肠—直肠癌(简称乙直肠癌)术后患者肠道功能恢复的疗效。【方法】将47例行乙直肠癌根治性手术后的患者随机分为治疗组28例和对照组19例。2组均给予术后常规治疗,包括给予禁食、胃肠减压、抗感染、支持对症处理。治疗组在术后常规治疗的基础上加用氧驱动雾化吸入中药加味枳术煎(由枳实、白术、厚朴、砂仁、大黄组成),每隔8 h 1次雾化吸入。观察并记录2组恢复自主肛门排气排便时间、肠鸣音恢复时间及胃肠减压引流量等情况。【结果】治疗组患者的恢复自主肛门排气排便时间、肠鸣音恢复时间显著缩短,胃肠减压引流液量较对照组显著减少(均P<0.05)。【结论】氧驱动雾化吸入加味枳术煎对促进乙直肠癌术后患者肠道功能恢复疗效确切。

Objective To observe the therapeutic effect of oxygenic force atomization inhalation of Modified Zhizhu Decoction on intestinal function recovery of postoperative patients with cancer of sigmoid colon and rectum （in short of colorectal cancer）. Methods Forty-seven cases of colorectal cancer who have received the radical surgery were divided into treatment group （N=28）and control group （N=19）. Both groups were given routine treatment such as fasting, gastrointestinal decompression, anti-infectious treatment and symptomatic treatment, and additionally treatment group was given oxygenic force atomization inhalation of Modified Zhizhu Decoction （mainly composed of Fructus Aurantii lmmaturus, Rhizoma Atractylodis Macrocephalae, Cortex Magnoliae Officinalis, Fructus Amomi, Radix et Rhizoma Rhei） every 8 hours. Time for the recovery of aerofluxus and defecation, time for the recovery of bowel sound, and the drainage volume after gastrointestinal decompression were observed in both groups. Results Time for the recovery of aerofluxus and defecation and time for the recovery of bowel sound were shortened, and the drainage volume after gastrointestinal decompression ~as decreased in the treatment group as compared with the control group （P〈0.05）. Conclusion Oxygenic force atomization inhalation of Modified Zhizhu Decoction shows certain effect on intestinal function recovery of postoperative patients with colorectal cancer.