新疆呼吸道感染患儿肺炎支原体抗体检测分析

Analysis of antibodies to Mycoplasma pneumonia in children with a respiratory infection in Xinjiang

目的探讨血清肺炎支原体(MP)抗体IgM在新疆地区呼吸道感染患儿的阳性检出率及其感染与民族和季节的关系。方法 2010年1月～2011年12月采用被动凝集法对14岁以下呼吸道感染患儿血清中肺炎支原体抗体IgM进行检测。结果 1 000例患儿MP IgM抗体阳性361例,阳性率为36.10%,在9种常见的患儿呼吸道感染性疾病中,支气管炎最高,为54.00%,先天性心脏病合并肺炎最低,为10.00%;各民族呼吸道感染患儿均检出MP阳性,以哈萨克族最高,阳性率为42.11%,汉族其次,为38.95%,维吾尔族最低,为20.69%;秋、冬季的MP抗体阳性率为40.00%,高于春、夏季(31.52%)。结论新疆地区呼吸道感染患儿MP感染率较高,检测MP IgM有利于对呼吸道感染病原体做出诊断,为治疗提供依据。

Objective To examine the relationship between infection with 2VIycoplasma pneumoniae and positive detec- tion of M. pneumoniae IgM in the sera of children with a respiratory tract infection in the Xinjiang region among ethnic groups and by season. Methods M. pneumoniae antibodies were detected in sera by passive agglutination. Data on M. pneumoniae IgM in 1 000 patients under the age of 14 with a respiratory tract infection from January 2010 to December 2011 were analyzed. Results The rate of M. pneumoniae antibody detection was 36.10% （361/1000）. Among 9 types of respiratory tract infections that were commonly found in the children, bronchitis was the most frequent （54.00%） while pneumonia accompanying congenital heart disease was the least frequent （10. 00%）. Among different ethnic groups, Kazakhs had the highest antibody detection rate （42.11 % ） while Uighurs had the lowest （20.69 % ）. The rate of M. pneumoniae infection was higher in the autumn and winter （40.00%） than in the spring and summer （31.52%）. Conclusion The Xinjiang Region has a high rate of M. pneumoniae infection in children with a respiratory tract infection. Kazakhs are most affected by M. pneumoniae and M. pneumoniae is more prevalent in the autumn and winter.