甲氨蝶呤联合米非司酮对输卵管妊娠的疗效探讨

The Efficacy of Methotrexate Combined with Mifepristone for Tubal Pregnancy

目的探讨甲氨蝶呤联合米非司酮对输卵管妊娠的临床治疗效果。方法选择我院2010年1月～2012年1月收治的输卵管妊娠患者98例,分为研究组和对照组各49例。研究组患者使用甲氨蝶呤联合米非司酮进行治疗;对照组的患者单纯使用甲氨蝶呤进行治疗。对比两组的治疗效果、治疗时间以及不良反应。结果研究组中总有效46例,占93.88%;对照组中总有效39例,占79.59%。研究组的治疗时间为7.6±1.5d,对照组为9.3±2.2d。研究组共发生不良反应5例,对照组12例。两组各结果相比,P<0.05,具有统计学差异。结论对输卵管妊娠的患者使用甲氨蝶呤联合米非司酮进行治疗,能有效的提高治疗效果,缩短治疗时间,值得在临床大范围使用。

Objective To discusses the efficacy of methotrexate combined with mifepristone for tubal pregnancyAlethods 98 cases of tubal pregnancy from January 2010 to January 2012 were chosen and divided into study group and control group, each group with 49 cases. Patients in study group were treated with methotrexate joint mifepristone, patients in control group were treated with methotrexate to compare the effect, treatment time and adverse reaction of two groups Results Total effective 46 cases in study group, accounting for 93.88% ;In the control group total effective 39 cases, accounting for 79.59%.The treatment time is （7.6±1.5）days, compared with （9.3±2.2）days. 5 cases had adverse reaction in study group, 12 cases in control group.There was significant difference in the two groups （P〈0.05）. Conclusion Tubal pregnancy patients with methotrexate joint mifepristone treatment, can effectively improve the treatment effect,short the treatment time, and deserve a wide range of use in clinical.