期刊文献+

骨肉瘤化疗进展 被引量:4

下载PDF
导出
摘要 骨肉瘤是最常见的原发性恶性骨肿瘤,占儿童和青少年恶性骨肿瘤的60%[1]。随着新型辅助化疗和手术治疗的开展,其5年存活率已经升高至50%~80%[1]。由于化疗抵抗的产生和化疗药物的不良反应,25%~50%的患者后期会出现转移和局部复发,严重影响治疗效果,常导致最终的死亡。本文就骨肉瘤的化疗进行述评,期望藉此了解骨肉瘤化疗的进展。
出处 《广东医学》 CAS CSCD 北大核心 2013年第7期1137-1139,共3页 Guangdong Medical Journal
  • 相关文献

参考文献24

  • 1MEYERS P A. Muramyl tripeptide (mifamurtide) for the treat- ment of osteosarcoma[ J]. Expert Rev Antieancer Ther, 2009, 9 (8) : 1035 -1049.
  • 2汪新媛,田京.骨肉瘤化疗研究进展[J].国际骨科学杂志,2010,31(3):159-161. 被引量:19
  • 3FERRARI S, SMELAND S, MERCURI M, et al. Neoadjuvant chem- otherapy with high -dose Ifosfamide, high -dose methotrexate, cispl- atin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups[J]. J Clin Oncol, 2005, 23(34) : 8845 -8852.
  • 4龚印华.新辅助化疗结合保肢手术治疗骨肉瘤的临床观察[J].肿瘤基础与临床,2012,25(3):221-223. 被引量:14
  • 5MEYERS P A, SCHWARTZ C L, KRAILO M D, et al. Osteosar- coma: the addition of muramyl - tripeptide to chemotherapy im- prove sover all survival: a report from the Children's Oncology Group[J]. J Clin Oncol, 2008, 26(4): 633 -638.
  • 6LONGHI A, FERRARI S, BACCI G, et al. Long - term follow - up of patients with doxorubicin - induced cardiac toxicity after chemotherapy for osteosarcoma [ J ]. Anticancer Drugs, 2007, 18 ( 6 ) : 737 - 744.
  • 7BASARAN M, BAVBEK E S, SAGLAM S, et al. A phase II study of eisplatin, if osfamide and epirubiein combination chemo- therapy in adults with non metastatic and extremity osteosarcomas [J]. Oncology, 2007, 72(3/4): 255 -260.
  • 8王翌庆,刘云霞.氨磷汀在骨肉瘤大剂量联合化疗中的骨髓保护作用[J].中国现代应用药学,2012,29(5):457-461. 被引量:7
  • 9JAFFE N, GORLICK R. High - dose methotrexate in osteosarco- ma : let the questions surcease time for final acceptance [ J ]. J Clin Oncol, 2008, 26 (27) : 4365 - 4366.
  • 10于秀淳,刘晓平,周银,李开华.MMIA术前化疗在骨肉瘤保肢术中的意义[J].肿瘤防治研究,2003,30(3):217-220. 被引量:18

二级参考文献102

共引文献91

同被引文献63

  • 1余卫平,绪广林,沈成兴,钱之玉.西红花酸对H_2O_2诱发心肌细胞凋亡及相关调控蛋白caspase-3、Bcl-2表达改变的影响[J].中国病理生理杂志,2006,22(1):54-57. 被引量:11
  • 2李焰生.中国后循环缺血的专家共识[J].中华内科杂志,2006,45(9):786-787. 被引量:1142
  • 3魏红,李劲松,刘文军.普通型骨肉瘤中C-kit受体的表达及意义[J].山东大学学报(医学版),2007,45(3):243-245. 被引量:2
  • 4Clucas J, Valderrama F. ERM proteins in cancer progression [ J ]. J Cell Sci, 2014, 127(Pt2) : 267 -275.
  • 5Donald G, Hertzer K, Eibl G. Baicalein-an intriguing therapeutic phytochemical in pancreatic cancer [ J ]. Curr Drug Targets, 2012, 13(14) : 1772-1776.
  • 6Naveenkumar C, Raghunandhakumar S, Asokkumar S, et al. Baicalein abrogates reactive caygen species (ROS)-rrediated n4tochondrial dysfunctima during experimental pulmonary carcinogenesis in vivo[ J]. Basic Clin Pharmacol Toxicol, 2013, 112(4) : 270-281.
  • 7Chen K, Zhang S, Ji Y, et al. Baicalein inhibits the invasion and metastatic capabilities of hepatocellular carcinoma cells via down-regulation of the ERK pathway [ J/OA. PLoS One, 2013, 8 (9) : e72927.
  • 8Zhang Y, Zhang L, Zhang G, et al. Ost metastasis: prospective role of ezfin[J]. Tumour Biol, 2014, 35(6) : 5055 -5059.
  • 9Adada M, Canals D, Hannun YA, et al. Sphingolipid regulation of ezrin, radixin, and moesin proteins family: implications for cell dynamics [ J ]. Biochim Biophys Acta, 2014, 1841 (5) : 727 - 737.
  • 10Parnell E, Yarwood SJ. Interactions between Epacl and ezrin in the control of endothelial barrier function [ J ]. Biochem Soc Trans, 2014, 42(2) : 274 -278.

引证文献4

二级引证文献17

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部