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地佐辛预防鼻咽手术全麻患者术后躁动的效果 被引量:14

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摘要 目的评价地佐辛预防鼻咽部手术全麻患者术后躁动的效果。方法择期行鼻咽部手术患者90例,随机分为3组:芬太尼组(F组)、地佐辛组(D组)和对照组(C组),每组30例。所有患者均采用静脉快速诱导及七氟醚复合瑞芬太尼维持麻醉。在手术结束前15 min,F组静脉注射芬太尼1μg/kg,D组静脉注射地佐辛0.1 mg/kg,C组静脉注射生理盐水5 mL。记录苏醒时间、拔除气管导管时间,记录苏醒后即刻(T1)、1 h(T2)、2 h(T3)时视觉模拟评分(VAS)、镇静评分(RAMSAY)和躁动评分(SAS),记录拔除气管导管后呼吸抑制、恶心呕吐的发生情况。结果 F组的苏醒时间和拔除气管导管时间均比D组和C组延长;与C组比较,F组和D组术后各时点的VAS评分明显降低,术后躁动评分明显降低(P<0.05),与F组比较,D组在T3时的VAS评分明显降低(P<0.05);与F组比较,D组和C组在T1、T2时的镇静评分明显降低,术后呼吸抑制发生率降低(P<0.01),3组患者恶心呕吐的发生率差异无统计学意义(P>0.05)。结论手术结束前15 min静脉注射地佐辛0.1 mg/kg可预防鼻咽部手术全麻患者的术后躁动,且不良反应较小。
出处 《广东医学》 CAS CSCD 北大核心 2013年第8期1277-1279,共3页 Guangdong Medical Journal
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