未分型自身免疫性胰腺炎13例临床分析

Clinical analysis on undifferentiated type of autoimmune pancreatitis in 13 cases

目的提高临床医生对自身免疫性胰腺炎的认识及诊疗水平。方法收集2011年6月至2012年11月该院收治的13例自身免疫性胰腺炎患者的临床资料,并进行回顾性分析。结果 13例患者均存在血清IgG水平升高,CT、磁共振胰胆管成像(MRCP)及内窥镜逆行胰胆管造影(ERCP)等影像学检查的异常表现,经糖皮质激素治疗后复查血液指标下降且影像学表现明显好转。结论自身免疫性胰腺炎是一种少见的慢性胰腺炎类型,且极易被误诊为胰腺癌,临床医生应提高对该病的认识,防止误诊,进而减少手术治疗。

Objective To enhance the clinician′s awareness of autoimmune pancreatitis and the level of diagnosis and treatment.Methods The clinical data of 13 cases of autoimmune pancreatitis treated in this hospital from June 2011 to November 2012 were collected and analyzed retrospectively.Results The serum concentration of IgG was increased and the abnormalimaging findings including CT,MRCP and ERCP existed in 13 cases.The hematologic parameters were reduced and the imaging findings were markedly improved after glucocorticoid therapy.Conclusion Autoimmune pancreatitis is a rare chronic pancreatitis which can easily be misdiagnosed as pancreatic cancer.Clinicians should increase the awareness of this disease,avoid misdiagnosis and reduce surgical treatment.