食盐加碘前后缺碘病区儿童生长发育调查

A study on children's growth in Chaohu iodine deficiency disorders district before and after universal salt iodization

目的 研究碘缺乏病区学龄儿童在全民食盐加碘前后生长发育状况。方法 对该地区 7～ 14岁儿童(食盐加碘前 2 47人 ,食盐加碘后 2 11人 )测定身高、下部量、体重 ,并计算 Roherer指数 ,测定尿碘。结果 食盐加碘前儿童尿碘中位数平均水平 2 6 .1μg/ L,其中 >10 0 μg/ L 者占 5 .4% ;食盐加碘后儿童尿碘中位数平均水平 384.7μg/ L,>10 0 μg/ L 者占 95 .2 %。提示碘营养差状态改善 (P <0 .0 0 1)为碘营养充足。食盐加碘后高年龄组儿童身高较食盐加碘前同年龄、同性别组儿童增加 ,尤以下部量为显著 (P <0 .0 5～ 0 .0 0 5 )。体重及单位体积体重(Roherer指数 )较食盐加碘前同年龄同性别儿童显著升高 (P <0 .0 5～ 0 .0 0 5 )。高年龄组见 Roherer指数与尿碘水平 (0 .5 5～ 10 0 3.6 7μg/ L 范围内 )显著正相关 (r =0 .5～ 0 .6 ,P <0 .0 0 5 )。结论 全民食盐加碘对儿童生长发育有促进作用并使原有的缺碘亚临床损伤得到改善。

Objective To investigate the children's growth before and after universal salt iodization (USI) in IDD district.Methods We measured the body height (BH),down-body height (DBH),body weight (BW) and urinary iodine of children who were randomly selected out from this district (before USI:247 persons;after USI:211 persons).Results The median urinary iodine (Mui) increased from 26.1 μg/L to 384.4 μg/L and the children whose Mui>100 μg/L increased from 5.4% to 95.2% after one year USI,showing the iodine deficient status had been improved.Children's DBH,BW and Roherer index of many age-and-sex-groups increased significantly than those of the same age-and sex-groups after USI(P<0.05~0.005).The urinary iodine level (0.55~ 1003.67 μg/L) had significant positive relationship with Roherer index in many age-and sex-groups  (P<0.005). Conclusions Universal salt iodization promotes the growth of children and corrects the sub-clinic damage of IDD.