克山病病区12例急性心肌炎临床病理分析

Clinical and pathological analysis of 12 cases of acute myocarditis in Keshan disease area

目的 探讨云南省克山病病区急性致死性心肌炎暴发流行及其猝死的原因。方法 对 12例在季节性群体发病中收集到的死亡病例 ,作临床病理资料总结分析。结果 此类心肌炎暴发流行具有一定的发病特点 ,心肌病变主要表现为间质性炎症反应 ,在 9例心肌组织中 ,有 8例肠道病毒 RNA阳性。结论 肠道病毒感染可能是云南克山病病区急性心肌炎暴发流行的主要病因。

Objective Study why acute and lethal myocarditis fulminate in Keshan disease area in Yunnan.Method Analyse clinical and pathological data of 12 dead cases in seasonal colonial invasion.Results There are some invasion characteristics about this kind of myocarditis.The pathologic change was major myocardial interstitium occuring inflammatory reaction.There were 8 cases enterovirus RNA positive out of 9 cases myocardium.Conclusions The primary cause for acute and lethal myocarditis fulminate in Keshan disease area in Yunnan is probablely enterovirus infection.