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蛋白激酶C与银屑病

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摘要 蛋白激酶C由多种同工酶组成 ,在人类表皮细胞中分布较为广泛。它一旦受到活化即在细胞的信号传导过程中起着重要作用 ,能调节细胞的生长与发育、细胞因子的产生和粘附分子的表达。在银屑病患者的表皮细胞中蛋白激酶C的活性及其表达均与正常表皮细胞中的不同。有研究表明蛋白激酶C参与触发银屑病 ,同时又与银屑病的病理生理存在着一定关系。据此可以提出治疗银屑病的新途径。
出处 《国外医学(皮肤性病学分册)》 2000年第4期213-215,共3页 Foreign Medical Sciences(Section of Dermatology and Venereology)
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