89例系统性红斑狼疮患者ENA、抗核抗体、抗dsDNA检测

Assay of serum ENA、ANA、anti-dsDNA on 89 patients with SLE

为了早期确诊系统性红斑狼疮 ,给临床诊断提供有力的证据 ,实验室检测了 89例临床上诊断为系统性红斑狼疮患者的血中 ENA、抗核抗体、抗 ds DNA。结果显示 :血中抗 Sm抗体检出率为 32 .5 8% ;抗核抗体检出率为 87% ;抗 ds DNA检出率为 73%。提示有必要将抗核抗体、ENA和 ds DNA抗体一同检测以免漏诊早期发病。

To accquire the accurate diagnosis of systemic lupus erythematosus (SLE) early, we performed tests of antinuclear antibody(ANA), antibody of extractable nuclear antigen(ENA) and antibody of double strand DNA (anti-dsDNA) in the serum on 89 patients with clinical diagnosis of SLE. The results are as follows:32.58% tested positive for anti-Sm antibody;87% tested positive for ANA;73% tested positive for anti dsDNA. The study suggested that the tests of ANA、ENA and anti-dsDNA should be performed simultane ously to avoid missing out the diagnosis of atypical or early stage SLE.