粒细胞集落刺激因子在肝硬化失代偿中的检测及临床意义

The study of granuilorte colonr stimulation factor in decompensated cirrhosis paitients

目的 观察粒细胞集落因子在肝硬化失代偿中的意义。方法 117例肝硬化失代偿病人分别采静脉血清、腹水 ,用ELISA法检测GCSF ,同时查血常规及腹水培养。结果 肝硬化失代偿病人血清及腹水中GCSF水平均升高 ,两者阳性率均与原发性腹膜炎密切相关 ,有腹膜炎的病人血清GCSF阳性率达 10 0 % (P <0 .0 1) ,腹水GCSF阳性率达 83.33% (P <0 .0 0 1) ,两者阳性率有显著的一致性 (P <0 .0 1)。结论 对发热、细菌培养阴性、粒细胞性及低蛋白性腹水 ,在达不到传统确定腹腔感染指标时 。

Objectives To study of Granulocyte(olony-Stimulatiny-Factor in decompensated cirrhosis patients.Methods 117 test results of blood and ascites used the ELISA from the patient with decompensated cirrhosis were respectively analysed.Results The GCSF levels of blood and ascites were higher in the patient with decompensated cirrhosis than the normal.And the GCSF of blood and ascites with decompensated cirrhosis than the normal.And the GCSF of blood and ascites with the patient of primary peritonitis following the decompensated cirrhosis were respectively 100% and 83.3%(P<0.01).Conclusions The GCSF of diagnosis the primary peritonitis following the patient with decompensated cirrhosis if the patien thave the fever,but ascites of bacteria culture were ngative,there were be found the cell central granular in ascites as Hypoproteinemia whose couldn′t be diagnosed the primary peritonitis used the traditional methods.So it is suggest that the patient with the higher GCSF should be treated with the Antibacterian early.