静脉代输尿管的研究

Study of vein substitute for ureter

目的 寻求比较理想的输尿管缺损代用材料。方法 用 2 4只成年山羊 ,手术取一侧长度为 2 .5～ 8.0cm输尿管 ,用同样长度静脉代替 ,在不同时期取代输尿管进行组织学检查。结果 静脉代输尿管长度在 3.0cm以下移植静脉可以成活 ,长度在 5 .0cm以下移植静脉在 8周内可被输尿管组织细胞完全代替 ,长度 6 .0～ 8.0cm移植静脉坏死后部分被纤维结缔组织代替 ,最终出现管壁厚 ,管腔狭窄 ,效果不佳。结论 静脉代替输尿管是一种较为理想的自身代用材料 ,对输尿管缺损 5 .0cm以下较为实用。

Objective To search for ideal replacement material for ureter defect. Methods 2.5～8.0 cm length ureters of one side were resected from 24 adult goats and replaced by the same length veins. Histological examination of the substituted ureter was made at different time points. Results The vein substitute for ureter less than 3.0 cm length could be alive. The substitute less than 5.0 cm could be replaced completely by ureter cells within 8 weeks. As the length of the substitute was 6.0 to 8.0 cm, the necrosis grafted vein was replaced partially by fibre connective tissue, resulting in the ureter wall being thicker and the lumen being stricture.Conclusion Vein is a relatively ideal self-substitute material for the replacement of ureter, and is more practical for ureter defect less than 5.0 cm length.