丹芪偏瘫胶囊疗效和安全性研究进展

Research progress about the efficacy and safety of Danqi Piantan Jiaonang

脑血管疾病是全球范围内致残率和死亡率较高的疾病之一，又名“中风”、“脑卒中”。尽管临床治疗中风有一些进步，但大多数患者预后不佳，急需找到一种治疗中风疗效更好的方法。在中国，传统中药制剂丹芪偏瘫胶囊已广泛用于临床以促进脑卒中的康复。中国医学界分别对比了丹芪偏瘫胶囊与步长脑心通胶囊（另一种治疗中风的中药制剂）、曲克卢丁（西药）、常规中风治疗的疗效与安全性。研究均表明，丹芪偏瘫胶囊治疗中风疗效确切并相对安全。而世界其他国家尤其是中东地区和东南亚，也纷纷对丹芪偏瘫胶囊的疗效与安全性进行了多样的评估，也证实丹芪偏瘫胶囊的疗效与安全性。该药的临床价值日益受到重视，需要更多大样本、随机双盲的多中心试验检验其疗效与安全性。

Cerebrovascular disease is a leading cause of disability and mortality worldwide. Despite improvements in acute stroke treatment, many patients only make a partial or poor recovery. Therefore, there is a need for treatments that would further improve outcome. Danqi Piantan Jiaonang, a traditional Chinese medicine, has been widely used in China for stroke recovery. Trials compared Danqi Piantan Jiaonang with Buchang Naoxintong Jiaonang, Troxerutin, or standard treatments of stroke have been conducteded in China. Danqi Piantan Jiaonang turned out to be more effective and relatively safe. The safety and effect of Danqi Pi- antan Jiaonang has also been variously assessed in other countries, particularly in South East Asia and Middle East. With the improvement of living standard and the development of health consciousness people pay much more attention to it. Therefore, there is a need for more larger, double-blind, randomized, multicenter trials to test the safety and efficacy of Danqi Piantan Jiaonang. Progress about the effect and safety of Danqi Piantan Jiaonang are reviewed.