胃镜下食管扩张术患者乳化依托咪酯-地佐辛麻醉的效果评价

Efficacy of etomidate combined with dezocine for esophageal dilatation by gastroscope

目的评价胃镜下食管扩张术患者乳化依托咪酯-地佐辛麻醉的效果。方法拟行食管扩张术患者60例,ASAⅠ～Ⅱ级,随机分为A、B组两组,每组30例,A组在乳化依托咪酯联合地佐辛静脉麻醉下行胃镜下食管扩张术,B组在清醒状态下行胃镜下食管扩张术。两组均于术前、中、后连续监测并记录血压(BP)、心率(HR)、动脉血氧饱和度(SPO2)、呼吸频率(RR)、不良反应、胃镜操作时间及术后总体满意度,并进行比较。结果 A组明显降低了术中不良反应的发生率,治疗时间较短,术后满意度高,与B组比较差异显著(P<0.05);B组术中、术后均有血压升高和心率增快,与B组术前和A组比较均有显著差异(P<0.05)。结论乳化依托咪酯-地佐辛麻醉用于胃镜下食管扩张术安全有效,值得推广应用。

Objective To evaluate the efficacy of etomidate （etomidate-lipuro, B. Braun） combined with dezoeine for esophageal dilatation by gastroscope. Methods Sixty cases of ASA I or II patients who were undergoing esophageal dilatation were randomly divided into two groups with 30 patients in each： etomidate ombined with dezocine （group A） and without anesthesia （group B）. BP, HR, RR and SPO2 were observed at three time point： preoperation,intraopera- tion and postoperation. The adverse reactions, gastroscopy time and total satisfactory degree after operation were also recorded. Results The incidences of the adverse reactions were significantly lower in group A than that in group B （P〈 0.05）, gastroscopy time was significantly shorter in group A than that in group B （P〈0. 05）. Total satisfactory degree after operation was higher in group A than that in group B （P〈0. 05） . Intraoperative and postoperative BP were significantly higher than in preoperative BP of group B and in group A （P〈0. 05） . Conclusion Etomidate ombined with dezocine for esophageal dilatation by gastroscope has safe and, effective anesthesia effect. It deserves further clinical applications.