甲状腺癌患者^(131)I治疗后唾液腺显影及损伤原因分析

Image and damage of salivary glands induced by ^(131)I treatment in patient with thyroid carcinoma

目的探讨甲状腺癌患者131I治疗后唾液腺显影及损伤的原因。方法 1例甲状腺癌患者,131I全身显像唾液腺显影,对唾液腺进行SPECT/CT融合显像和超声检查。结果 SPECT/CT融合显像、唾液腺超声提示左侧慢性腮腺炎。结论甲状腺癌患者131I治疗后唾液腺显影和损伤,与唾液腺小叶导管上皮细胞膜钠碘同向转运体摄取131I,131I发射β射线使细胞发生坏死有关,要密切观察及监测唾液腺功能。

Objectivet To evaluate the image and damage of salivary gland induced by 1311 treatment in patient with thyroid carcinoma. Methods One case of thyroid cancer, for left salivary gland developing in 131I whole body imaging, were examined SPECT/CT fusion imaging and ultrasound of salivary glands. Results Left chronic parotitis was proved by fusion imaging and ultrasound. Conclusion 131I used to treat thyroid cancer patient is taken up by the salivary glands for sodium iodine symporter. β-radiation from 131I exerts cytotoxic effects in the salivary glands.