1Nguyen HB,SmithD. Sepsis in the 21 st century: recent defini- tions and therapeutic advances[J]. Am J Emerg Med,2007,25 (5)564-571.
2Levy MM,Fink MP, Marshall JC. 2001 SCCM/ESICM/AC-CP/ ATS/SIS International Sepsis Definitions Conference[J]. Inten- sive Care Meal,2009,29(4) :530-538.
3Balk RA. Severe sepsis and septic shock, Definitions, epidemiolo- gy and clinical manifestationsl-J]. Crit Care Clin, 2000, 16:179-202.
4Martin GS,Mannino D M, Eaton S, et al. 0The epidemiology oI sepsis in the United States from 1979 through 2000 EJ-. N Engl J Med, 2003,348 : 1546-1554.
5Baoli Cheng,Guo Hao Xi e,Shang long Yao,et al. Epidemiology of severe sepsis in critically ill Sursical patients in ten university hospital in China[J]. Crit Care Med,2008,35(11) : 1-10.
7Martin GS, Mannino DM, Eaton S, et al. The epidemiology of sepsis in the United States from 1979 through 2000 [J]. N Engl ] Med, 2003,348 : 1546-1554.
8Ilva E, DA [meida PM, Sogayar AC, et al. Brazilian Sepsis Epide- miolocal Study(BASES study) [J]. Crit Care, 2004, 8: R251- 260.
4Blank C, Luz A, Bendigs S, et al. Superantigen and endotoxin synergize in the induction of lethal shock. Eur J Immunol, 1997, 27:825-833.
5Bourrie B, Benoit JM, Derocq JM, et al. A sigma ligand, SR31747A, potently modulates Staphylococcal enterotoxin B-induced cytokine production in mice. Immunology, 1996, 88: 389-393.
6Li HY, Yao YM, Shi ZG, et al. The potential role of Staphylococcal enterotoxin B in rats with postburn Staphylococcus aureus sepsis. Shock, 2003, 20: 257-263.
7Cooney RN. Suppressors of cytokine signaling (SOCS): inhibitors of the JAK/STAT pathway. Shock, 2002, 17: 83-90.
8Opal SM, Cohen J. Clinical gram-positive sepsis: does it fundamentally differ from gram-negative bacterial sepsis? Crit Care Med, 1999, 27: 1608-1616.