康复新液管饲治疗婴幼儿应激性溃疡的疗效观察

The observation of effect of Kangfuxin solution in the treatment of stress ulceration in infants

目的观察康复新液治疗婴幼儿应激性溃疡的疗效。方法 60例应激性溃疡随机分成治疗组和对照组各30例,两组在治疗原发病、奥美拉唑抑制胃酸分泌的基础上,治疗组管饲康复新液10mg,每6小时1次,对照组管饲去甲肾上腺素0.25mg+NS10ml,每6小时1次,观察两组临床治疗效果。结果治疗组总有效率90.0%,对照组总有效率66.7%,两组比较差异具有统计学意义(P<0.05)。治疗组止血时间、循环不良消失时间、胃肠功能紊乱消失时间均短于对照组,差异均有统计学意义(P<0.01)。结论康复新液管饲治疗婴幼儿应激性溃疡疗效显著,并可缩短止血时间,简单、价廉,未见明显不良反应,值得临床推广使用。

Objective To observe the effect of Kangfuxin solution in the treatment of stress ulceration in infants. Methods 60 cases of stress ulceration in infants were randomly divided into a treatment group and a control group with ：30 patients in each group. Both groups were given omeprazole, and their primary diseases were treated as well. Addition- ally, the treatment group were given Kangfuxin solution 10mg through tube feeding, once every 6 hours and the control group received norepinephrine 0.25mg＋NS 10mL through tube feeding, once every 6 hours. The effective rate and hemostasis time were examined to evaluate the therapeutic effect. Results The total effective rate was 90. 0% in treatment group and 66. 7% in control group. The difference between the two groups was significant （P〈0.05）. The hemostasis time and the disappearance time of poor circulation and gastrointestinal disorders of the treatment group were shorter than those of the control group, the differences were statistically significant （P 〈 0.01）. Conclusion Kangfuxin solution through tube feeding for stress ulceration in infants can obviously improve the clinical efficacy and effectively shorten the hemostasis time. As an easy, cheap therapy, Kangfuxin solution through tube feeding can be widely used for stress ulceration and bleeding in clinical practice. There is no obvious adverse reaction.