部分脾动脉栓塞治疗地中海贫血12例疗效观察

Observation on the effect of partial splenic artery embolization on 12 thalassemia cases

目的探讨部分脾动脉栓塞术(PSE)治疗地中海贫血的疗效及临床意义。方法对12例地中海贫血患者行部分脾动脉栓塞术,观察术前和术后的血象变化、脾脏大小及并发症情况。结果显示全部患儿临床表现明星改善,术后2周及1个月复查血常规,HGB有显著升高(P<0.01),脾脏3个月后较前缩小。结论PSE治疗地中海贫血是安全有效。

Objective To assess the therapeutic effect and clinical significance of partial splenic artery embolization （ PSE） in the treatment of thalassemia cases. Methods Twelves cases was treated with PSE. the preoperative and postopera- tive variations of hemogram thalassemia spleen size and postoperative complications were observed. Results The resuhs of blood routine examination two weeks and a month after the operation, revealed that HGB increased significantly （P〈0.01）.The spleen size shrank three months after treatment. Conclusion PSE is effective and safe in treatment of PSE..