血液复检的临床意义

Clinical significance of blood retest post collection

目的 :为了探讨造成血液复检不合格的原因 ,减少血源性疾病的传播 ,笔者将 2 10 6 4袋血液的复检结果进行了统计分析。方法 :复检项目中转氨酶 (alaninetransaminase ,ALT)按照一般酶测定原理进行测定。乙型肝炎表面抗原 (hepatitisBsurfaceantigen ,HBsAg)、丙肝病毒抗体 (anti hepatitisCvirus ,抗 HCV)和爱滋病病毒抗体(anti humanimmunodeficiencyvirus,抗 HIV)均采用酶联免疫吸附法进行检测 ;梅毒血清试验采用传统的快速血浆反应素法 (rapidplasmareagin ,RPR)。结果 :血液复检不合格率为 1 0 5 1% ,不合格的主要原因是转氨酶的轻度增高和丙肝抗体阳性。乙肝复检不合格者极少 ,仅占复检血液的 0 2 98% ,已经不是输血后肝炎的主要原因了。转氨酶 +乙肝表面抗原和转氨酶 +丙肝抗体两项阳性率均为零 ,说明急性乙型和丙型肝炎患者已被初检筛选。结论 :为了保证受血者安全 ,杜绝血源性疾病的传播 。

Objective:In order to seek the main causes for the blood retest post collection and to decrease the occurrence of diseases transmitted by blood transfusion, we perform the statistics and analysis on the retest of 21 064 units of blood. Methods:Of all the items carried out in blood retest, ALT is tested according to the general principle on enzyme examine. As to the items of HBsAg、anti HCV and anti HIV, method of ELISA is used. Syphilis is checked with rapid plasma reagin. Results:The rate of unqualified blood unit is about 1 051%. The results of the unqualified retest blood units are mainly caused by slightly increased level of ALT and the positivity of anti HCV. The unqualified blood on account of the positivity of HBsAg only has a small fraction of 0 299%, which makes little contribution to the heapititis of posttransfusion. In addition, no positivity of ALT+HBsAg or ALT+anti HCV tells us that the donor with acute heapititis B or C has been checked out in first test. Conclusion:Retest of blood is necessary in order to protect the blood recipients from suffering the transfusion transmitted diseases.