转化糖电解质注射液对胃肠道肿瘤患者围术期血糖及电解质的影响

Effects of invert sugar and electrolytes injection on the blood glucose and electrolyte of patients with gastro- intestinal cancer during peri-operation period

目的观察转化糖电解质注射液对于胃肠道肿瘤患者围术期血糖及电解质的影响。方法将116例胃肠道手术患者完全随机分为观察组和对照组，各58例，分别给予转化糖电解质和10％葡萄糖注射液500ml静脉滴注，观察2组患者给药前及给药后0、1、2h的血糖、电解质及血尿酸水平，并记录并发症发生率。结果①观察组患者给药后0、1h血糖[分别为（6．7±1．1）、（6．0±0．9）mmol／L]均较给药前[（4．9±0．5）mmol／L]明显升高（P〈0．05）；给药后2h血糖[（5．1±0．7）mmol／L]接近给药前水平（P〉0．05）；对照组患者给药后0、1、2h血糖[分别为（9．8±1．9）、（8．3±1．3）、（6．9±1．1）mmol／L]均较给药前[（5．0±0．5）mmo]／L]明显升高（P〈0．05）；给药后0、1、2h，观察组血糖水平均明显低于对照组同时间点，组间差异均有统计学意义（均P〈0．05）。②观察组给药后血K＋、Na＋、Cl-、Ca2＋水平与给药前的差异无统计学意义（P〉0．05），对照组给药后0、1、2h血K＋水平[分别为（3．7±0．4）mmol／L、（3．7±0．4）mmol／L、（3．7±0．3）mmol／L]均低于给药前[（3．9±0．4）mmol／L]，（P〈0．05）；2组Na＋、Cl-、Ca2＋水平与本组给药前的差异均无统计学意义（P〉0．05）；观察组给药后0、1、2h血K＋水平[分别为（4．1±0．4）、（4．0±0．5）、（4．0±0．5）mmol／L]均高于对照组同时间点水平（P〈0．05）。2组患者血尿酸水平差异无统计学意义（P〉0．05）。结论转化糖电解质注射液对于胃肠道肿瘤患者围术期血糖稳定以及补钾的疗效更优，且安全可靠。

Objective To observe the effects of invert sugar and electrolytes injection on the blood glucose and electrolyte of patients with gastrointestinal cancer during peri-operation period. Methods One hundred and six- teen cases of patients with gastrointestinal operation were randomly divided into the observation group and the control group and then were treated with sugar and electrolytes and glucose injection in 10% of 500 ml. The glucose, elec- trolytes and blood uric acid levels before transfusion and after infusion in 0, 1,2 h and complications in two groups were obeserved. Results The blood glucose and fluctuated K ~ level in observation group were significantly lower than those in the control group during operation period; other indices fluctuated in different levels, but had no statis- tically significance （P 〉 0. 05 ）; no serious complications occured in two groups and safety were similar. Conclusion The effects of invert sugar and electrolytes injection on blood glucose and the level of potassium of pa- tients with gastrointestinal tumor is optimistic.