肝内胆管癌的诊治进展

Diagnosis and therapy of intrahepatic cholangiocarcinomas

肝内胆管癌是胆管上皮细胞癌的一种，其发病与肝内胆管结石、病毒性肝炎、原发性硬化性胆管炎、Caroli病、寄生虫感染等有关，近年来，其发病率逐渐升高。超声、CT、MRI检查都可以用于该病的诊断。目前肝内胆管癌主要的治疗方式是以肝切除为主的综合治疗。肝移植治疗肝内胆管癌仍有一定的争议。辅助疗法对无法接受手术的肝内胆管癌患者将越来越重要。

Intrahepatic cholangiocarcinomas is a type of biliary epithelial cell carcinoma. Hepatolithiasis, viral hepatitis, primary sclerosing cholangitis, Caroli disease, parasitic infections are its risk factors. In recent years, the incidence of intrabepatic cholangiocarcinomas is gradually increased. Ultrasound, CT, MRI can be used to diag- nose. The main way to treat intrahepatic cholangioearcinomas is comprehensive treatment based on liver resection. There is still some controversy in liver transplantation. Adjuvant therapy will play a more and more important role in patients who unable to accept surgery.