苏州大学附属常熟医院专项整治前后抗菌药物应用分析

Antibiotic Use in Changshu Hospital Affiliated to Soochow University before and after Special Rectification

目的:了解开展"全国抗菌药物临床应用专项整治活动"前后抗菌药物使用情况,为临床合理用药提供参考。方法:采用回顾性调查方法,调取2011年1—6月(整治前)和7—12月(整治后)抗菌药物品种、用量和销售金额,对其销售金额和用药频度(DDDs)进行统计、分析。结果:抗菌药物销售金额和DDDs在整治后均有所下降。整治后特殊使用级抗菌药物销售金额(万元)和DDDs分别占全部药品的8.15%(2.42/2 973.16)和0.79%(4 455/567 093)。整治后销售金额排序居前3位的药品分别为头孢地秦钠、头孢西丁钠和氨曲南;DDDs排序居前3位的药品为克拉霉素、头孢呋辛酯和洛美沙星。结论:我院抗菌药物应用渐趋合理,但仍需进一步提高合理用药水平。

OBJECTIVE：To probe into the antibiotic use before and after carrying out the Special Rectification Activities of Clinical Application of Antibacterials in China in order to provide reference for clinical rational drug use. MEHTODS：A retrospective study was conducted in which drug kinds,consumption amount,consumption sum （10 000 Yuan） and DDDs of antibaeterials in our hospital in the first half year of 2011 （before intervention） and the second half year of 2011 （ after intervention ） were collected for statistical analysis. RESULTS ： After intervention, both the consumption sum and DDDs of antibacterials showed reduction. Of the total drugs consumed, the antibacterials for special use after intervention represented 8.15 % （2.42/2 973.16） in consumption sum and 0.79% （4 455/567 093 ） in DDDs. The top 3 antibacterials on the list of consumption sum after intervention were cefodizime sodium, cefoxitin sodium and aztreonam. The top 3 antibacterials on the list of DDDs were clarithromycin, cefuroxime axetil and lomefloxacin. CONCLUSION：The use of antibacterials in our hospital became more and more rational, yet the rational drug use level remains to be improved further.