(4-(嘧啶-2-基)哌嗪基)(2-苯基喹唑啉)甲酮的绿色合成

Green Method Synthesis of (2-phenylquinazolin-4-yl)(4-(pyrimidin-2-yl)piperazin-1-yl)methanone

采用4-氯-2-苯基喹啉、嘧啶哌嗪等为原料,经过取代、水解、缩合等反应,绿色合成方法合成了(4-(嘧啶-2-基)哌嗪基)(2-苯基喹唑啉)甲酮,并对其结构用1HNMR和MS进行了表征。

（2-phenylquinazolin-4-yl）（4-（pyrimidin-2-yl）piperazin-1-yl）methanone was synthesized with 4-chloro-2-phenyl-quinoline,pyrimidine piperazine,etc by substitution reaction,hydrolysis and condensation reaction,via a green synthesis method,The structure of the title compound was characterized by1HNMR and MS.