阿托伐他汀钙联合羟乙基淀粉针治疗分水岭脑梗死临床疗效研究

Clinical Research on the Effect of Atorvastatin Calcium Combined with Hydroxyethyl Starch Needle in the Treatment of Watershed Infarction

目的探究和分析联合使用羟乙基淀粉针和阿托伐他汀钙治疗分水岭区脑梗死的临床疗效。方法抽取我院2008年至2011年确诊为分水岭脑梗死的患者128例,将其分为A、B两组各64例;A组给予阿托伐他汀钙联合羟乙基淀粉针治疗,B组仅采用阿托伐他汀钙进行治疗;分析比较两组患者不同时间的疗效及预后情况。结果经过一周的治疗后,A组患者好转人数多于B组患者;A组患者中出现肺部感染、上消化道出血及脑血管后抑郁症的人数较B组少;患者经30天治疗后,A组患者达到痊愈的人数较B组多。以上数据经统计学分析,P均<0.05,具有统计学意义。结论阿托伐他汀钙联合羟乙基淀粉针治疗分水岭脑梗死临床疗效良好,临床可以考虑进一步推广。

Objective To explore and analyze the joint use of the hydroxyethyl starch needle and Atorvastatin calcium in the treatment of watershed infarction. Methods 128 patients with watershed infarction in our hospital from 2008 to 2011 were selected and divided into two groups. Group A received the treatment of hydroxyethyl starch needle combined with Atorvastatin calcium, while group B received the Atorvastatin calcium alone. The treatment effect and prognosis of two groups were analyzed retrospectively. Results After treatment for one week, the improved case of group A was more than that of group B; the patients with lung infection, upper gastrointestinal bleeding or cerebrovascular depression of group A was fewer than that of group B; After treatment for 30 days, the cure rate of group A was higher than that of group B. All the differences were statistically significant （P 〈0.05）. Conclusions The treatment of Atorvastatin calcium combined with hydroxyethyl starch needle for watershed infarction has good clinical curative effect, which is worthy of clinical application.