血凝状态与进展性脑梗死的关系探讨

Relationship between Coagulation State and Progressive Cerebral Infarction

目的：探讨凝血状态与进展性脑梗死的关系。方法：固态法测定凝血各项指标。比较进展性脑梗死、非进展性脑梗死及对照组之间的差异。结果：脑梗死患者的血浆纤维蛋白原（FIB）及D-二聚体（D—DL）含量较对照组均明显升高（P〈0．05），进展性脑梗死患者高于非进展性脑梗死患者，差异有统计学意义（P〈0．05）。结论：进展性脑梗死患者存在着明显的高凝状态，凝血指标的异常与病情的进展密切相关。

OBJECTIVE： To explore the relationship between the coagulation state and progressive cerebral infarction. METHODS ： The coagulation indicators were determined by solid - state method. The diversity was compared among progressive cerebral in- farction, non - progressive cerebral infarction and control group. RESULTS ： The levels of plasma fibrinogen （FIB） and D - dimer （ D - DL） in progressive group and non - progressive group were higher than that in the healthy control group （P 〈 0. 05）. And the levels in progressive group were higher than that in non -progressive group. There was statistically significant difference between the two groups （P 〈 0. 05）. CONCLUSIONS： The patients with progressive cerebral infarction have the hypercoagulable state. Abnormal coagulation indicators is closely related to the progress of the disease.