FDG-PET在骨与软组织恶性肿瘤临床诊治中的应用
摘要
骨与软组织恶性肿瘤早期诊断和预防复发一直是临床骨科治疗难题。骨与软组织肿瘤发生于骨内或起源于骨各种组织成分及运动系统其他结构,有一般肿瘤的代谢功能特征。利用18氟脱氧葡萄糖正电子断层成像(FDG-PET)技术功能性显像特点早期诊断骨与软组织恶性肿瘤并排查远处转移病灶,对临床治疗具有实践意义。该文就FDG-PET技术在骨与软组织恶性肿瘤早期分级及局部复发、远处转移、治疗反应和预后预测方面的研究进展作一综述。
出处
《国际骨科学杂志》
2013年第3期196-199,共4页
International Journal of Orthopaedics
参考文献34
-
1Garcia R,Kim EE,Wong FC,et al.Comparison of fluorine-18-FDG PET and technetium-99m-MIBI SPECT in evaluation of musculoskeletal sarcomas[J].J Nucl Med,1996,37(9):1476-1479.
-
2Watanabe H,Shinozaki T,Yanagawa T,et al.Glucose metabolic analysis of musculoskeletal tumours using 18fluorine-FDG PET as an aid to preoperative planning[J].J Bone Joint Surg Br,2000,82(5):760-767.
-
3Kern KA,Brunetti A,Norton JA,et al.Metabolic imaging of human extremity musculoskeletal tumors by PET[J].J Nucl Med,1998,29(2):181-186.
-
4Feldman F,van Heertum R,Manos C.18FDG PET scanning of benign and malignant musculoskeletal lesions[J].Skeletal Radiol,2003,32(4):201-208.
-
5Iagaru A,Quon A,McDougall IR,et al.F-18 FDG PET/CT evaluation of osseous and soft tissue sarcomas[J].Clin Nucl Med,2006,31(12):754-760.
-
6Ozulker T,Kucukoz-Uzun A,Ozulker F,et al.Comparison of 18F-FDG-PET/CT with 99mTc-MDP bone scintigraphy for the detection of bone metastases in cancer patients[J].Nucl Med Commun,2010,31(6):597-603.
-
7Mahajan A,Woo SY,Kornguth DG,et al.Multimodality treatment of osteosarcoma:radiation in a high-risk cohort[J].Pediatr Blood Cancer,2008,50(5):976-982.
-
8Bajpai J,Kumar R,Sreenivas V,et al.Prediction of chemotherapy response by PET-CT in osteosarcoma:correlation with histologic necrosis[J].Pediatr Hematol Oncol,2011,33(7):e271-e278.
-
9Mortazavi-Jehanno N,Giraudet AL,Champion L,et al.Assessment of response to endocrine therapy using FDG PET/CT in metastatic breast cancer:a pilot study[J].Eur J Nucl Med Mol Imaging,2012,39(3):450-460.
-
10London K,Stege C,Cross S,et al.18F FDG PET/CT compared to conventional imaging modalities in pediatric primary bone tumors[J].Pediatr Radiol,2012,42(4):418-430.
-
1欧阳学农.长期腰痛需排查肺癌[J].大家健康,2009(1):62-62.
-
2李敏.老年人患肿瘤有什么特点[J].老年健康,2007(5):17-17.
-
3李桂枝,刘静,史丽民.原发性腹膜后肿瘤的手术治疗[J].医学理论与实践,2001,14(7):655-656.
-
4张晓飞,殷秋芳.CA125联合CA153检测用于老年乳腺恶性肿瘤诊断中临床意义分析[J].中国高等医学教育,2012(9):138-139. 被引量：1
-
5章必成,高建飞.M2型巨噬细胞:肿瘤治疗的新靶点[J].临床误诊误治,2012,25(4):64-66. 被引量：6
-
6安刚,齐军元,邱录贵.外周T细胞淋巴瘤的治疗进展[J].中华血液学杂志,2008,29(10):718-720. 被引量：4
-
7Gambrell R D,郭志义.老年妇女癌症的诊断和预防[J].国外医学（肿瘤学分册）,1989,16(3):169-171.
-
8高姗,杨万水,高静,王静,项永兵.原发性肝癌的分子流行病学研究进展[J].中国肿瘤,2012,21(2):136-144. 被引量：28
-
9靳风烁.膀胱肿瘤复发相关问题的研究进展[J].中华外科杂志,2009,47(10):723-724. 被引量：1
-
10Gambrell RD,齐玉琴.老年妇女癌的诊断和预防[J].国外医学（老年医学分册）,1989,10(5):207-209.
