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IL-17在再生障碍性贫血中的研究进展 被引量:1

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摘要 再生障碍性贫血(aplasticanemia,AA)是一种常见的骨髓造血衰竭症,其发病原因仍不清楚,目前被认为疾病主要与患者骨髓增生能力降低,免疫异常和造血功能减少等有关。其中,免疫细胞的异常活化和增多发挥至关重要的作用。传统的观点认为,AA患者存在免疫异常,免疫细胞Thl/Th2失衡,向Thl偏移,I型淋巴因子分泌增多,促进和导致造血负调控因子大量产生,从而直接或间接损伤造血干细胞,最终骨髓造血功能衰竭。
作者 陆翔 李红文
出处 《右江医学》 2013年第2期272-274,共3页 Chinese Youjiang Medical Journal
基金 百色市科学研究与技术开发计划项目(百科计20120122)
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参考文献16

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二级参考文献28

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