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母血浆游离胎儿DNA检测在无创性产前诊断中的应用 被引量:1

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摘要 母血浆细胞游离胎儿DNA(cell-free fetal DNA,cffDNA)在无创性产前诊断中的研究取得了很大的进展,如文献报道可用于诊断性连锁遗传病、Rh血型不合、基因组印迹和某些染色体疾病等。目前的研究主要是对常见非整倍体疾病的诊断,已有多种通过cffDNA的检测对非整倍体疾病进行无创性产前诊断的方法见于报道。
作者 张有成
出处 《中国优生与遗传杂志》 2013年第5期1-2,5,共3页 Chinese Journal of Birth Health & Heredity
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  • 1Lo YMD, Corbetta N, Chamberlain PF, et al. Presence of fetal DNA in maternal plasma and serum[J]. Lancet,1997,350:485 487.
  • 2Alberry M, Maddocks D, Jones M, et al. Free fetal DNA in maternal plasma in anembryonic pregnancies : confirmation that the origin is the trophoblast[ J]. Prenat Diagn,2007 ,27: 415 - 418.
  • 3Chan KC, Zhang J, Hui AB, et al. Size distributions of maternal and fetal DNA in maternal plasma[J]. Clin Chem,2004,50:88 - 92.
  • 4Birch L, English CA, O'Donoghue K, et al. Accurate and robust quantification of circulating fetal and total DNA in maternal plasma from 5 to 41 weeks of gestation [ J ]. Clin Chem,2005,51 : 312.
  • 5Rijnders R J, Cbristiaens GC, Soussan AA, et al. Cell - free fetal DNA is not present in plasma of nonpregnant mothers [ J ]. Clin Chem, 2004,50:697 - 681.
  • 6Lo YMD, Tein MS, Lau TK, et al. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive pre- natal diagnosis[J]. Am J Hum Genet,1998 ,62: 768 - 775.
  • 7Lo YMD. Fetal DNA in maternal plasma[ J ] Ann NY Aead Sei, 2000,906:141 - 147.
  • 8Dhallan R, Au WC, Mattagajasingh S, et al. Methods to increase the percentage of free fetal DNA recovered from the maternal circulation [J]. JAMA, 2004,291:1114 1119.
  • 9Costa JM, Benachi A, Gautier E, et al. First - trimester fetal sex de- termination in maternal serum using real -time PCR[ J]. Prenat Di- agn,2001,21: 1070 - 1074.
  • 10Lo YMD, Hjelm NM, Fidler C, et al. Prenatal diagnosis of fetal RhD status by molecular analysis of maternal plasma [ J ]. N Engl J Med, 1998,339: 1734 - 1738.

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