摘要
目的探讨性别、年龄、BMI对高血压患者动脉僵硬度的影响。方法从上海市宝山区6家社区卫生中心及上海市第三人民医院入选1026例单纯高血压患者,收集病史信息,检测其颈一股动脉脉搏波速度(C—FPwV)。672例患者在随访一年后完成复测。从性别、年龄、BMI的不同水平进行分组比较及随访前后对照分析。结果(1)男性组C—FPwV高于女性组,分别为(13.63±3.07)m/s和(12.59±2.85)m/s(P〈0.01)。一年后两组C—FPwV均增快,男性为(14.11±3.58)m/s,女性(13.51±3.56)m/s(P〈0.05)。(2)30~50岁、〉50~70岁、〉70岁三组C—FPWV随年龄增大而增快,分别为(11.11±2.00)m/s、(12.73±2.77)m/s、(14.74±3.29)m/s(P〈0.01)。1年后3组的C—FPwV均增快,分别为(11.36±1.78)m/s(P〉0.05)、(13.39±3.33)m/s(P〈0.01)和(15.68±3.94)m/s(P〈0.05),C-FPwV增幅依次为:〉70岁组、〉50~70岁组、30~50岁组。(3)BMI/〉24krJm。组较BMI〈24kg/m。组C—FPwV略低,分别为(12.93±2.89)m/s和(13.39±3.18)m/s(P〈0.05)。1年后C—FPwV值均有增高,分别为(13.54±3.54)m/s,(14.27±3.61)m/s(P〈0.01)。结论除BMI外,性别、年龄均为动脉僵硬度的重要影响因素。
Objective To investigate the influences of gender, age, and body mass index (BMI) on the arterial stiffness in hypertensive patients. Methods A total of 1026 hypertensive patients were en- rolled in this study from 6 community health centers in Baoshan District and Shanghai Third People~ Hospi- tal. The Related medical histories and carotid-femoral(C-F) pulse wave velocity (PWV) were recorded and PWV were re-tested in 672 patients after 1 yearg follow-up. The C-F PWV was analyzed from different group of Gender, age and BMI at baseline and after follow up. Results (1)C-F PWV of the male hypertensive pa- tients were higher than that of female's and the corresponding figures were (13.63 ± 3.07 )m/s and (12. 59 ±2. 85)m/s( P 〈 0. 0) ). After one year% follow up, C-F PWV was increased in both male and female with corresponding figures of ( 14. 11 ±3.58)m/s and ( 13.51 ±3.56)m/s( P 〈0. 05). (2) The C-F PWV was increased with age. The corresponding figures were [ ( 11.11 ± 2. 00) m/s for age group 30 - 50 years old, (12.73 ±2.77)m/s for age group 〉50 -70 years old, and (14.74 ±3.29)m/s for age group 〉70 years old, all P 〈 0. O1 ]. After one year's follow-up, C-F PWV of three age groups was increased and the corresponding figures were [(11.36 ±l.78)m/s(P 〉0.05), (13.39 ±3.33)m/s( P 〈0.01), and ( 15.68 ±3.94)m/s( P 〈0. 05) ]. The increased range of C-F PWV (from high to low) was age group 〉 70, age group 〉 50 -70 and age group 30 -50. (3) C-F PWV of patients with BMI ≥24 kg/m2 was signifi- cantly lower than that of patients with BMI 〈 24 kg/m2 and the corresponding figures were [ ( 12. 93 ± 2. 89 ) m/s and ( 13.39 ± 3.18 ) m/s, P 〈 0.05 ]. After one yearg follow up, C-F PWV was increased and the fig-ures were [(13.54±3.54)m/sand (14.27±3.61) m/s, respectively( P 〈0.01)]. Conclusions Ex- cept BMI, gender and age were the important influence factors on arterial stiffness.
出处
《中国医师杂志》
CAS
2013年第4期465-468,共4页
Journal of Chinese Physician
基金
上海申康医院发展中心适宜技术联合开发推广项目(SHDCl2007226)