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替格瑞洛抗血小板治疗的疗效观察 被引量:7

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摘要 抗血小板治疗是ACS必不可少的基本治疗,但也有其局限性。多国多中心的GRACE注册临床研究显示,ACS患者1年后死亡率约为15%,3年后升高至25%,4年后可达39%。在目前的治疗方法中,因CYP2C19基因多态性的问题,导致有些患者存在氯吡格雷抵抗或低反应,影响治疗效果;而且,在东亚人群中,该比例还高于西方人群,对于这部分药物抵抗人群,目前尚缺乏肯定有效的办法。
作者 闫睿
出处 《中国循证心血管医学杂志》 2013年第2期138-138,共1页 Chinese Journal of Evidence-Based Cardiovascular Medicine
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