期刊文献+

两岁以下婴幼儿重型颅脑损伤的临床特点与治疗 被引量:3

Treatment and Clinical Characteristics of Severe Traumatic Brain Injury in Infants under Two Years Old
原文传递
导出
摘要 目的:探讨两岁以下婴幼儿重型颅脑损伤的临床特点与有效治疗方法。方法:2007年1月至2011年12月期间,我科收治两岁以下婴幼儿重型颅脑损伤患儿24例,其中合并其他部位损伤10例。外伤后均有程度不等的意识障碍,改良GCS评分为3~8分,其中5分以下6例,5~8分18例;呕吐13例,瞳孔变化9例,抽搐或癫痫发作9例。保守治疗16例,手术治疗8例。采用格拉斯哥预后评分(GOS)标准评价治疗效果。结果:24例患儿出院时疗效良好率66.7%(16/24),死亡率16.7%(4/24);出院后12个月疗效良好率达70.8%(17/24),死亡率达20.8%(5/24)。入院时GCS改良评分与出院后GOS评分之间呈显著正相关。结论:两岁以下婴幼儿有其特有的生理特点,颅脑损伤后意识障碍、生命体征变化、呕吐、癫痫发作等全身症状严重,对失血敏感,治疗有其特殊性,积极治疗可望改善预后。
出处 《解剖与临床》 2013年第2期146-148,共3页 Anatomy and Clinics
  • 相关文献

参考文献8

二级参考文献45

共引文献25

同被引文献59

  • 1刘建雄,毛伯镛.影响小儿重型颅脑损伤预后的危险因素分析[J].中华小儿外科杂志,2005,26(1):14-16. 被引量:14
  • 2Klose MC, Juul A, Poulsgaard L,et al.Pituitary insufficiency following head trauma.Ugeskr Laeger. 2007;169(3):211-213.
  • 3Protheroe RT, Gwinnutt CL.Early hospital care of severe traumatic brain injury.Anaesthesia. 2011 ;66(11 ): 1035-1047.
  • 4Ahmed Z, Dent RG, Suggate EL,et al.Disinhibition of neurotrophin-induced dorsal root ganglion cell neurite outgrowth on CNS myelin by siRNA-mediated knockdown of NgR, p75NTR and Rho-A.Mol Cell Neurosci. 2005;28(3): 509-523.
  • 5Li L, Ding J, Marshall C,et al.Pretraining affects Morris water maze performance with different patterns between control and ovariectomized plus D-galactose-injected mice.Behav Brain Res. 2011 ;217(1 ):244-247.
  • 6Grigorian AS, Gilerovich EG, Pavlichenko NN,et al.Effect of transplantation of mesenchymal stem cells on neuronal survival and formation of a glial scar in the brain of rats with severe traumatic brain injury.Bull Exp Biol Med. 2011 ;150(4) 551-555.
  • 7Titomanlio L, Kavelaars A, Dalous J,et al.Stem cell therapy for neonatal brain injury: perspectives and challenges.Ann Neurol. 2011 ;70(5):698-712.
  • 8Jones GL, Juszczak MT, Hughes SJ,et al.An improved method of fluorescent dual insulin and endothelial staining allows visualisation of the revascularisation of intraportally transplanted islets.Transplant Proc. 2005;37(8):3509-3511.
  • 9Ha Y, Choi JU, Yoon DH,et al.Neural phenotype expression of cultured human cord blood cells in vitro.Neuroreport. 2001; 12(16):3523-3527.
  • 10Buzanska L, Jurga M, Domanska-Janik K.Neuronal differentiation of human umbilical cord blood neural stem-like cell line.Neurodegener Dis. 2006;3(1-2):19-26.

引证文献3

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部