n-HA/PA66复合材料融合器在后路经椎间孔腰椎椎体间融合术中的应用研究

Applied research of n-HA/PA66 cage used in transforaminal lumbar interbody fusion

目的分析纳米羟基磷灰石/聚酰胺66(n-HA/PA66)复合材料融合器在治疗腰椎退行性疾病中的作用及效果。方法应用n-HA/PA66复合材料融合器对20例腰椎退行性疾病行经椎间孔腰椎椎体间融合术(TLIF),通过测量术前、术后1周、术后2个月腰椎曲线指数、相对椎间隙高度、Tailard指数、节段前凸角、全腰椎前凸角等影像学检查指标及Gree-nough临床疗效标准等,评价手术疗效。结果除了Tailard指数,其余影像学观察指标术后1周、术后2个月与术前比较,差异均有统计学意义(P<0.01667)。在腰痛、腿痛,术前、术后1周、术后2个月三者之间两两比较差异均有统计学意义(P<0.01667)。根据Greenough临床疗效标准评估临床效果,疗效优良率达95%,术后无严重并发症。结论 n-HA/PA66复合材料融合器可有效治疗腰椎退行性疾病,可防止椎间高度塌陷下沉、解除神经根受压,是一种疗效理想的椎间融合器材料。

Objective To analyze the applied research of n-HA/PA66 cage used in the transforaminal lumbar interbody fusion. Methods All of 20 patients with lumbar regressive disease were treated by the transforaminal lumbar interbody fusion （TLIF） with n-HMPA66 cage. The clinical results were retrospectively analyzed before operation, one week and two months after operation. Follow up included relative height of vertebral space, Taillard index, index of lumbar spinal curvature, angle of segmental and full lordosis. The clinical effects were evaluated according to the standard of Greenough and VAS. Results Except Taillard index, all the observed values were improved. Back pain and leg pain were also improved. According to the Greenough clinical standard, the excellence rate was 95%. Conclusion Conclusion n-HA/PA66 cage is an effective method in the treatment of lumbar regressive disease, regains and avoids decreasing the space between two vertebrals, eliminates the press of the nerve and is the ideal material of the cage.