复方丹参滴丸联合阿司匹林治疗不稳定型心绞痛的临床疗效研究

Clinical effect research of compound danshen dripping pills combined with aspirin in the treatment of unstable angina pectoris

目的探讨复方丹参滴丸与阿司匹林联合应用治疗不稳定型心绞痛的临床疗效,为临床用药提供依据。方法将2012年3～12月在我院接受治疗的80例不稳定型心绞痛患者按就诊的不同时间和治疗方法分为对照组40例和联合治疗组40例。对照组患者采用阿司匹林进行常规治疗,联合治疗组患者在对照组的治疗基础上加用复方丹参滴丸,舌下含服或口服,4周后比较两组临床疗效。结果两组患者经治疗后,对照组患者显效12例,有效19例,无效9例,总有效率为77.5%;联合治疗组患者显效15例,有效23例,无效2例,总有效率为95.0%,联合治疗组效果优于对照组,差异具有统计学意义(P<0.05)。结论复方丹参滴丸与阿司匹林联合应用治疗不稳定型心绞痛疗效显著,其效果明显优于单纯的阿司匹林用药,此法值得在临床上合理推广。

Objective To investigate the clinical effect of Compound Danshen dripping pills with aspirin in the treatment of unstable angina pectoris, provide the basis for clinical medication. Methods 80 cases of patients with unstable angina pectoris from 2012 March-2012 year in December treated in our hospital were divided into the control group of 40 cases and combined treatment group of 40 cases according to different time and methods of treatment.The control group was treated with conventional aspirin,combined treatment group were treated with Compound danshen dripping pills on basis of conventional therapy,sublingual or oral,after 4 weeks the clinical efficacy of two groups were compared. Results After the treatment,12 cases is excellent in control group,efficient 19 cases,invalid 9 cases the total efficiency was 77.5%;combined treatment group excellent 15 cases,effective 23 cases,invalid 2 cases,the total efficiency of 95.0%, the effect of combined treatment group was better than the control group,with significant difference（P 〈 0.05）. Conclusion The effect of compound danshen dripping pills with aspirin in the treatment of unstable angina pectoris is better significant ly than simple aspirin treatment,worthy of reasonable clinical promotion.