摘要
（E）-2-（1-（2-Hydroxy-4-methoxyphenyl）ethylideneamino）-3-（4-hydroxyphenyl）methyl propionate （C22H27O6N, Mr = 401.45） has been synthesized by a condensation reaction of paeonol with tyrosin methyl ester hydrochloride, and its structure was determined by IR, NMR, HR MS and X-ray single-crystal diffraction. The crystal belongs to the monoclinic system, space group P21/c, with a = 11.91291（15）, b = 9.49947（12）, c = 19.8727（3） , β = 106.1104（15）°, V = 2160.60（5）3, Z = 4, Dc = 1.234 g/cm3, μ = 0.739 mm-1, F（000） = 856, R = 0.0466 and wR = 0.1461 for 3859 observed reflections with （Ⅰ〉 2σ（Ⅰ））. In the crystal structure, the title compound is constructed by a centrosymmetric dimmer unit composed of a pair of π-π stacking enantiomers, and such units are linked by intermolecular O（5）-H（5）…O（1） and intramolecular N（1）-H（1）…O（1） hydrogen bonds.
（E）-2-（1-（2-Hydroxy-4-methoxyphenyl）ethylideneamino）-3-（4-hydroxyphenyl）methyl propionate （C22H27O6N, Mr = 401.45） has been synthesized by a condensation reaction of paeonol with tyrosin methyl ester hydrochloride, and its structure was determined by IR, NMR, HR MS and X-ray single-crystal diffraction. The crystal belongs to the monoclinic system, space group P21/c, with a = 11.91291（15）, b = 9.49947（12）, c = 19.8727（3） , β = 106.1104（15）°, V = 2160.60（5）3, Z = 4, Dc = 1.234 g/cm3, μ = 0.739 mm-1, F（000） = 856, R = 0.0466 and wR = 0.1461 for 3859 observed reflections with （Ⅰ〉 2σ（Ⅰ））. In the crystal structure, the title compound is constructed by a centrosymmetric dimmer unit composed of a pair of π-π stacking enantiomers, and such units are linked by intermolecular O（5）-H（5）…O（1） and intramolecular N（1）-H（1）…O（1） hydrogen bonds.
基金
Supported by the National Natural Science Foundation of China (No. 21072178)
Innovation Specialist Projects of Henan Province(No. 114200510023)
Innovation Scientists and Technicians Troop Construction Projects of Zhengzhou City (No. 112PLJRC359)
